Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | NT5E | P21589 | 1/20 | 0.50 |
| ▸ | PNP | P00491 | 3/20 | 0.49 |
| ▸ | HPRT1 | P00492 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | ALB | P02768 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | TGM2 | P21980 | 1/20 | 0.47 |
| ▸ | FUT5 | Q11128 | 1/20 | 0.46 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.46 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.46 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.46 |
| ▸ | HINT1 | P49773 | 1/20 | 0.44 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.43 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.43 |
| ▸ | KRAS | P01116 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22352199 | 1.00 | POLB (0.53) | POLBNT5EPNPHPRT1ALDH1A1 | |
| SCHEMBL16144103 | 0.90 | POLB (0.56) | POLBNT5EPNPHPRT1ALDH1A1 | |
| SCHEMBL21417495 | 0.90 | POLB (0.59) | POLBNT5EPNPHPRT1ALDH1A1 | |
| SCHEMBL18837841 | 0.90 | POLB (0.59) | POLBNT5EPNPHPRT1ALDH1A1 | |
| SCHEMBL3894678 | 0.90 | POLB (0.59) | POLBNT5EPNPHPRT1ALDH1A1 | |
| SCHEMBL20758514 | 0.90 | POLB (0.59) | POLBNT5EPNPHPRT1ALDH1A1 | |
| SCHEMBL19145773 | 0.89 | POLB (0.56) | POLBNT5EPNPHPRT1ALDH1A1 | |
| SCHEMBL20762962 | 0.88 | POLB (0.54) | POLBNT5EPNPHPRT1ALDH1A1 | |
| SCHEMBL20762967 | 0.88 | POLB (0.54) | POLBNT5EPNPHPRT1ALDH1A1 | |
| SCHEMBL23679527 | 0.88 | POLB (0.56) | POLBNT5EPNPHPRT1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020165600-A1 | BICYCLIC PEPTIDE LIGAND STING CONJUGATES AND USES THEREOF | BICYCLETX LIMITED (GB) | 2020-08-20 | — | — | WO | disclosed |