Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 12/20 | 0.84 |
| ▸ | LMNA | P02545 | 2/20 | 0.84 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.84 |
| ▸ | RAPGEF3 | O95398 | 2/20 | 0.84 |
| ▸ | GMNN | O75496 | 1/20 | 0.84 |
| ▸ | BLM | P54132 | 1/20 | 0.84 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.84 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.84 |
| ▸ | PDE4A | P27815 | 3/20 | 0.72 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.72 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.72 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.72 |
| ▸ | MEN1 | O00255 | 1/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.70 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10239776 | 0.96 | STING1 (0.76) | STING1LMNAKMT2ARAPGEF3GMNN | |
| Cyclic Adenosine Monophosphate SCHEMBL20912149 | 0.92 | STING1 (1.00) | STING1LMNAKMT2ARAPGEF3GMNN | |
| SCHEMBL22434642 | 0.92 | STING1 (1.00) | STING1LMNAKMT2ARAPGEF3GMNN | |
| Cyclic Adenosine Monophosphate SCHEMBL18716062 | 0.92 | STING1 (1.00) | STING1LMNAKMT2ARAPGEF3GMNN | |
| Cyclic Adenosine Monophosphate SCHEMBL23829591 | 0.92 | STING1 (1.00) | STING1LMNAKMT2ARAPGEF3GMNN | |
| Cyclic Adenosine Monophosphate SCHEMBL23829820 | 0.92 | STING1 (1.00) | STING1LMNAKMT2ARAPGEF3GMNN | |
| Cyclic Adenosine Monophosphate SCHEMBL23829670 | 0.92 | STING1 (1.00) | STING1LMNAKMT2ARAPGEF3GMNN | |
| Cyclic Adenosine Monophosphate SCHEMBL23829673 | 0.92 | STING1 (1.00) | STING1LMNAKMT2ARAPGEF3GMNN | |
| Cyclic Adenosine Monophosphate SCHEMBL23829653 | 0.92 | STING1 (1.00) | STING1LMNAKMT2ARAPGEF3GMNN | |
| Cyclic Adenosine Monophosphate SCHEMBL16446050 | 0.92 | STING1 (1.00) | STING1LMNAKMT2ARAPGEF3GMNN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020165600-A1 | BICYCLIC PEPTIDE LIGAND STING CONJUGATES AND USES THEREOF | BICYCLETX LIMITED (GB) | 2020-08-20 | — | — | WO | disclosed |