SCHEMBL22352207

SCHEMBL22352207

CC(C)SP1(=O)OC[C@H]2O[C@@H](n3cnc4c(N)ncnc43)C[C@@H]2OP(=O)(S)OCC2O[C@@H](n3cnc4c(N)ncnc43)C[C@@H]2O1

nearest known ligand 0.62

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ STING1 Q86WV6 19/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22352215 0.90 STING1 (0.65) STING1
SCHEMBL22352235 0.90 STING1 (0.65) STING1
SCHEMBL20763201 0.89 STING1 (0.77) STING1
SCHEMBL24624852 0.84 STING1 (0.73) STING1
SCHEMBL23798951 0.84 STING1 (0.89) STING1
SCHEMBL20763495 0.82 STING1 (0.65) STING1
SCHEMBL24323017 0.81 STING1 (0.66) STING1
SCHEMBL23477418 0.81 STING1 (0.65) STING1
SCHEMBL20692277 0.81 STING1 (0.65) STING1
SCHEMBL20691397 0.81 STING1 (0.65) STING1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020165600-A1 BICYCLIC PEPTIDE LIGAND STING CONJUGATES AND USES THEREOF BICYCLETX LIMITED (GB) 2020-08-20 — — WO disclosed
Send feedback