Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNJ5 | P48544 | 5/20 | 0.64 |
| ▸ | KCNJ3 | P48549 | 5/20 | 0.64 |
| ▸ | KCNJ6 | P48051 | 4/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | POLB | P06746 | 1/20 | 0.64 |
| ▸ | THRB | P10828 | 1/20 | 0.64 |
| ▸ | P2RX4 | Q99571 | 13/20 | 0.54 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19576804 | 0.85 | KCNJ5 (0.62) | KCNJ5KCNJ3KCNJ6ALDH1A1LMNA | |
| SCHEMBL24763839 | 0.84 | KCNJ5 (0.60) | KCNJ5KCNJ3KCNJ6ALDH1A1LMNA | |
| SCHEMBL19552065 | 0.83 | P2RX4 (0.71) | KCNJ5KCNJ3KCNJ6ALDH1A1LMNA | |
| SCHEMBL29718827 | 0.83 | P2RX4 (0.71) | KCNJ5KCNJ3KCNJ6ALDH1A1LMNA | |
| SCHEMBL19576873 | 0.83 | KCNJ5 (0.60) | KCNJ5KCNJ3KCNJ6ALDH1A1LMNA | |
| SCHEMBL19551509 | 0.81 | KCNJ5 (0.58) | KCNJ5KCNJ3KCNJ6ALDH1A1LMNA | |
| SCHEMBL19551508 | 0.81 | KCNJ5 (0.58) | KCNJ5KCNJ3KCNJ6ALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL19552593 | 0.80 | KCNJ5 (0.57) | KCNJ5KCNJ3KCNJ6ALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL19552592 | 0.80 | KCNJ5 (0.57) | KCNJ5KCNJ3KCNJ6ALDH1A1LMNA | |
| SCHEMBL20929094 | 0.80 | P2RX4 (0.57) | KCNJ5KCNJ3KCNJ6ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3458443-B1 | AROMATIC SULFONAMIDE DERIVATIVES | Bayer Pharma AG (DE) | 2020-08-19 | — | — | EP | disclosed |