Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 20/20 | 0.57 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24258718 | 0.88 | NR1H4 (0.62) | NR1H4NR1I2CYP2C9CYP2C19 | |
| SCHEMBL22353773 | 0.88 | NR1H4 (0.75) | NR1H4 | |
| SCHEMBL22348270 | 0.86 | NR1H4 (0.77) | NR1H4NR1I2CYP2C9CYP2C19 | |
| SCHEMBL22348335 | 0.85 | NR1H4 (0.77) | NR1H4NR1I2CYP2C9CYP2C19 | |
| SCHEMBL31316180 | 0.85 | NR1H4 (0.77) | NR1H4NR1I2CYP2C9CYP2C19 | |
| SCHEMBL24258925 | 0.85 | NR1H4 (0.73) | NR1H4NR1I2CYP2C9CYP2C19 | |
| SCHEMBL24259033 | 0.82 | NR1H4 (0.73) | NR1H4NR1I2CYP2C9CYP2C19 | |
| SCHEMBL24258753 | 0.81 | NR1H4 (0.64) | NR1H4NR1I2CYP2C9CYP2C19 | |
| SCHEMBL22353814 | 0.79 | NR1H4 (0.75) | NR1H4NR1I2CYP2C9CYP2C19 | |
| SCHEMBL24258942 | 0.79 | NR1H4 (0.73) | NR1H4NR1I2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020168143-A1 | SUBSTITUTED BICYCLIC COMPOUNDS AS FARNESOID X RECEPTOR MODULATORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2020-08-20 | — | — | WO | disclosed |