Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR2 | O43614 | 20/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22355742 | 1.00 | HCRTR2 (0.66) | HCRTR2 | |
| SCHEMBL22355744 | 1.00 | HCRTR2 (0.66) | HCRTR2 | |
| SCHEMBL22355736 | 0.88 | HCRTR2 (0.64) | HCRTR2 | |
| SCHEMBL24799823 | 0.86 | HCRTR2 (0.63) | HCRTR2 | |
| SCHEMBL22355735 | 0.86 | HCRTR2 (0.67) | HCRTR2 | |
| SCHEMBL22355825 | 0.86 | HCRTR2 (0.67) | HCRTR2 | |
| SCHEMBL22355835 | 0.86 | HCRTR2 (0.67) | HCRTR2 | |
| SCHEMBL22355839 | 0.84 | HCRTR2 (0.57) | HCRTR2 | |
| SCHEMBL22355740 | 0.84 | HCRTR2 (0.68) | HCRTR2 | |
| SCHEMBL24411363 | 0.83 | HCRTR2 (0.89) | HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020167701-A1 | PYRROLIDINE OREXIN RECEPTOR AGONISTS | MERCK SHARP & DOHME CORP. (US) | 2020-08-20 | — | — | WO | disclosed |