Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | SLC26A4 | O43511 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ACACB | O00763 | 2/20 | 0.36 |
| ▸ | ACACA | Q13085 | 2/20 | 0.36 |
| ▸ | GCK | P35557 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2235743 | 1.00 | MAOB (0.43) | MAOBMAOANR4A2NPC1RAB9A | |
| SCHEMBL2234792 | 0.91 | MAOB (0.47) | MAOBMAOANR4A2NPC1RAB9A | |
| SCHEMBL2234795 | 0.91 | MAOB (0.47) | MAOBMAOANR4A2NPC1RAB9A | |
| SCHEMBL2234783 | 0.91 | MAOB (0.47) | MAOBMAOANR4A2NPC1RAB9A | |
| SCHEMBL13582548 | 0.84 | MAOB (0.45) | MAOBMAOANR4A2NPC1RAB9A | |
| SCHEMBL13582543 | 0.84 | MAOB (0.45) | MAOBMAOANR4A2NPC1RAB9A | |
| SCHEMBL13582546 | 0.84 | MAOB (0.45) | MAOBMAOANR4A2NPC1RAB9A | |
| SCHEMBL13582395 | 0.82 | MAOB (0.43) | MAOBMAOANR4A2NPC1RAB9A | |
| SCHEMBL13582401 | 0.82 | MAOB (0.43) | MAOBMAOANR4A2NPC1RAB9A | |
| SCHEMBL2231836 | 0.82 | MAOB (0.41) | MAOBMAOANR4A2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011093524-A1 | DI - SUBSTITUTED PYRIDINE DERIVATIVES AS ANTICANCERS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2011-08-04 | — | — | WO | disclosed |