Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | TYMS | P04818 | 4/20 | 0.54 |
| ▸ | POLA1 | P09884 | 1/20 | 0.53 |
| ▸ | POLD1 | P28340 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL223586 | 1.00 | POLB (0.55) | POLBTYMSPOLA1POLD1 | |
| Water SCHEMBL6421677 | 0.99 | POLB (0.54) | POLBTYMSPOLA1POLD1 | |
| Water SCHEMBL6421666 | 0.99 | POLB (0.54) | POLBTYMSPOLA1POLD1 | |
| SCHEMBL1501320 | 0.91 | DTYMK (0.52) | POLBTYMSPOLA1POLD1 | |
| SCHEMBL12712223 | 0.88 | POLB (0.59) | POLBTYMSPOLA1POLD1 | |
| SCHEMBL16053561 | 0.87 | POLB (0.60) | POLBTYMSPOLA1POLD1 | |
| SCHEMBL16053560 | 0.87 | POLB (0.60) | POLBTYMSPOLA1POLD1 | |
| SCHEMBL20074275 | 0.87 | POLB (0.60) | POLBTYMSPOLA1POLD1 | |
| SCHEMBL8371071 | 0.87 | POLB (0.62) | POLBTYMSPOLA1POLD1 | |
| SCHEMBL1763106 | 0.87 | POLB (0.62) | POLBTYMSPOLA1POLD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 232 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8614302-B2 | Modified carbocyanine dyes and their conjugates | Life Technologies Corporation (US) | 2013-12-24 | — | — | US | claimed |
| EP-2151506-B1 | Method of amplifying target nucleic acid sequence by multiple displacement amplification including thermal cycling | SAMSUNG ELECTRONICS CO LTD (KR) | 2013-04-17 | — | — | EP | claimed |
| US-20100035303-A1 | Method of Amplifying Target Nucleic Acid Sequence By Multiple Displacement Amplification Including Thermal Cycling | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2010-02-11 | — | — | US | claimed |
| EP-2151506-A1 | Method of amplifying target nucleic acid sequence by multiple displacement amplification including thermal cycling | Samsung Electronics Co., Ltd. (KR) | 2010-02-10 | — | — | EP | claimed |
| US-20080057499-A1 | Methods for high specificity whole genome amplification and hybridization | AFFYMETRIX, INC. (US) | 2008-03-06 | — | — | US | claimed |
| US-7057031-B2 | Nucleotide compositions comprising photocleavable markers and methods of preparation thereof | AMBERGEN, INC. (US) | 2006-06-06 | — | — | US | claimed |
| US-6977148-B2 | Multiple displacement amplification | QIAGEN GMBH (DE) | 2005-12-20 | — | — | US | claimed |
| US-20040161742-A1 | Nucleic acid amplification | QIAGEN GMBH (DE) | 2004-08-19 | — | — | US | claimed |
| US-20030118998-A1 | Nucleic acid amplification | QIAGEN GMBH (DE) | 2003-06-26 | — | — | US | claimed |
| US-12571798-B2 | Cancer biomarkers and methods of use thereof | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2026-03-10 | — | — | US | disclosed |
| US-12332245-B2 | Cancer biomarkers and methods of use thereof | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2025-06-17 | — | — | US | disclosed |
| EP-3796002-B1 | CANCER BIOMARKERS AND METHODS OF USE THEREOF | UNIV CALIFORNIA (US) | 2023-11-22 | — | — | EP | disclosed |
| US-20230204591-A1 | CANCER BIOMARKERS AND METHODS OF USE THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2023-06-29 | — | — | US | disclosed |
| EP-3341377-B1 | POLYFLUORENO[4,5-CDE]OXEPINE CONJUGATES AND THEIR USE IN METHODS OF ANALYTE DETECTION | AAT BIOQUEST INC (US) | 2021-07-28 | — | — | EP | disclosed |
| US-5413924-A | For use in various in vitro chemical, biochemical and immunological reactions | KOSAK KENNETH M (US) | 1995-05-09 | — | — | US | disclosed |
| EP-0626017-A1 | HEAT-RELEASABLE REAGENTS FOR $i(IN VITRO) CHEMICAL REACTIONS | KOSAK, Kenneth M. (US) | 1994-11-30 | — | — | EP | disclosed |
| WO-1994008046-A1 | HISTONE mRNA OLIGONUCLEOTIDE PROBES | UNIVERSITY OF LEICESTER (GB) | 1994-04-14 | — | — | WO | disclosed |
| WO-1993016200-A1 | HEAT-RELEASABLE REAGENTS FOR IN VITRO CHEMICAL REACTIONS | KOSAK KENNETH M (US) | 1993-08-19 | — | — | WO | disclosed |
| US-5215882-A | METHOD OF IMMOBILIZING NUCLEIC ACID ON A SOLID SURFACE FOR USE IN NUCLEIC ACID HYBRIDIZATION ASSAYS | ORTHO DIAGNOSTIC SYSTEMS, INC. (US) | 1993-06-01 | — | — | US | disclosed |
| EP-0435470-A1 | Method of immobilizing nucleic acid on a solid surface for use in nucleic acid hybridization assays | ORTHO DIAGNOSTIC SYSTEMS INC. (US) | 1991-07-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12571798-B2 | Cancer biomarkers and methods of use thereof | MKI67, BRCA1, CD68 | POLB 4084/4885TYMS 3985/4885POLA1 3413/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.