Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 15/20 | 0.45 |
| ▸ | IL6 | P05231 | 5/20 | 0.45 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.44 |
| ▸ | TLR8 | Q9NR97 | 4/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26347753 | 0.88 | TLR7 (0.59) | TLR7IL6TLR8 | |
| SCHEMBL22359353 | 0.80 | TLR7 (0.58) | TLR7IL6TLR8 | |
| SCHEMBL26347233 | 0.78 | TLR7 (0.63) | TLR7IL6TLR8 | |
| SCHEMBL26347786 | 0.78 | TLR7 (0.61) | TLR7IL6TLR8 | |
| SCHEMBL26347245 | 0.78 | TLR7 (0.62) | TLR7IL6TLR8 | |
| SCHEMBL26347230 | 0.77 | TLR7 (0.60) | TLR7IL6TLR8 | |
| SCHEMBL26347256 | 0.77 | TLR7 (0.60) | TLR7IL6TLR8 | |
| SCHEMBL29475703 | 0.77 | TLR7 (0.60) | TLR7IL6TLR8 | |
| SCHEMBL28663619 | 0.77 | TLR7 (0.65) | TLR7IL6TLR8 | |
| SCHEMBL29475679 | 0.76 | TLR7 (0.60) | TLR7IL6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020168017-A1 | COMPOSITIONS CONTAINING, METHODS AND USES OF ANTIBODY-TLR AGONIST CONJUGATES | AMBRX, INC. (US) | 2020-08-20 | — | — | WO | disclosed |