Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.33 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8862807 | 1.00 | TDP1 (0.39) | TDP1LMNAMAPTTSHRMEN1 | |
| SCHEMBL8100476 | 0.98 | TDP1 (0.40) | TDP1LMNAMAPTTSHRMEN1 | |
| SCHEMBL7651937 | 0.92 | TDP1 (0.43) | TDP1LMNAMAPTTSHRMEN1 | |
| SCHEMBL12967483 | 0.85 | TDP1 (0.33) | TDP1MEN1KMT2ACA2 | |
| SCHEMBL7651938 | 0.84 | MAPT (0.40) | TDP1LMNAMAPTTSHRMEN1 | |
| SCHEMBL1401407 | 0.84 | MEN1 (0.44) | TDP1LMNAMAPTTSHRMEN1 | |
| SCHEMBL1401325 | 0.84 | MEN1 (0.44) | TDP1LMNAMAPTTSHRMEN1 | |
| SCHEMBL7900784 | 0.82 | TDP1 (0.38) | TDP1LMNAMAPTTSHRMEN1 | |
| SCHEMBL25868407 | 0.82 | TDP1 (0.57) | TDP1LMNAMAPTTSHRMEN1 | |
| SCHEMBL23997455 | 0.82 | TDP1 (0.34) | TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3924361-B1 | NOVEL TRITERPENE DERIVATIVES AS HIV INHIBITORS | HETERO LABS LTD (IN) | 2023-09-06 | — | — | EP | disclosed |
| WO-2020165741-A1 | NOVEL TRITERPENE DERIVATIVES AS HIV INHIBITORS | HETERO LABS LIMITED (IN) | 2020-08-20 | — | — | WO | disclosed |