SCHEMBL22360641

SCHEMBL22360641

N#Cc1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(-c4ccccc4)cc3)n2)cc1

nearest known ligand 0.60

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ABCG2 Q9UNQ0 13/20 0.60
ABCB1 P08183 7/20 0.60
CYP11B2 P19099 1/20 0.53
GABRA1 P14867 1/20 0.53
GABRG2 P18507 1/20 0.53
GABRB3 P28472 1/20 0.53
GABRA5 P31644 1/20 0.53
GABRA3 P34903 1/20 0.53
ALDH1A3 P47895 1/20 0.53
ABCC1 P33527 3/20 0.53
TSHR P16473 1/20 0.52
MYC P01106 1/20 0.49
MMP3 P08254 1/20 0.48
L3MBTL1 Q9Y468 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22106575 1.00 ABCG2 (0.60) ABCG2ABCB1CYP11B2GABRA1GABRG2
SCHEMBL20396079 1.00 ABCG2 (0.60) ABCG2ABCB1CYP11B2GABRA1GABRG2
SCHEMBL19939304 1.00 ABCG2 (0.60) ABCG2ABCB1CYP11B2GABRA1GABRG2
SCHEMBL22883053 1.00 ABCG2 (0.60) ABCG2ABCB1CYP11B2GABRA1GABRG2
SCHEMBL23384091 1.00 ABCG2 (0.60) ABCG2ABCB1CYP11B2GABRA1GABRG2
SCHEMBL23383904 1.00 ABCG2 (0.60) ABCG2ABCB1CYP11B2GABRA1GABRG2
SCHEMBL19939303 1.00 ABCG2 (0.60) ABCG2ABCB1CYP11B2GABRA1GABRG2
SCHEMBL23383850 1.00 ABCG2 (0.60) ABCG2ABCB1CYP11B2GABRA1GABRG2
SCHEMBL31663591 0.98 ABCG2 (0.62) ABCG2ABCB1CYP11B2GABRA1GABRG2
SCHEMBL22414164 0.94 ABCG2 (0.59) ABCG2ABCB1CYP11B2GABRA1GABRG2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020166825-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DIODE COMPRISING SAME 주식회사 엘지화학 2020-08-20 WO disclosed