SCHEMBL2236079

SCHEMBL2236079

CCCc1ccccc1C.[SiH3]O[SiH3]

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 1/20 0.54
KMT2A Q03164 1/20 0.40
DAO P14920 2/20 0.39
CA12 O43570 1/20 0.39
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
CA7 P43166 1/20 0.39
CA9 Q16790 1/20 0.39
CA14 Q9ULX7 1/20 0.39
CTBP2 P56545 1/20 0.38
TSHR P16473 1/20 0.38
ACHE P22303 1/20 0.38
CHRM2 P08172 1/20 0.37
PTGS1 P23219 1/20 0.37
PTGS2 P35354 1/20 0.37
MAPT P10636 1/20 0.37
GPR84 Q9NQS5 1/20 0.37
P2RX7 Q99572 1/20 0.36
ADRA2A P08913 1/20 0.36
ADRA2B P18089 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5496466 0.91 TAAR1 (0.62) TAAR1KMT2ADAOCA12CA1
SCHEMBL29462889 0.91 TAAR1 (0.62) TAAR1KMT2ADAOCA12CA1
SCHEMBL282555 0.91 TAAR1 (0.62) TAAR1KMT2ADAOCA12CA1
Water SCHEMBL27889910 0.89 TAAR1 (0.60) TAAR1KMT2ADAOCA12CA1
SCHEMBL9360089 0.83 TAAR1 (0.54) TAAR1KMT2ADAOCA12CA1
SCHEMBL27943143 0.80 TAAR1 (0.47) TAAR1KMT2ADAOCA12CA1
SCHEMBL8598519 0.79 TAAR1 (0.50) TAAR1KMT2ADAOCA12CA1
Phenol SCHEMBL28184726 0.79 TAAR1 (0.50) TAAR1KMT2ADAOCA12CA1
SCHEMBL28730038 0.78 TAAR1 (0.54) TAAR1KMT2ADAOCA12CA1
Methoxymethane SCHEMBL22720615 0.78 TAAR1 (0.54) TAAR1KMT2ADAOCHRM2PTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110190467-A1 Biological Polysiloxanes VISION CRC LIMITED (AU) 2011-08-04 US disclosed
US-20090276042-A1 Biological Polysiloxanes VISION CRC LIMITED (AU) 2009-11-05 US disclosed
EP-2021399-A1 BIOLOGICAL POLYSILOXANES VISION CRC LIMITED (AU) 2009-02-11 EP disclosed
WO-2007128051-A1 BIOLOGICAL POLYSILOXANES VISION CRC LIMITED (AU) 2007-11-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090276042-A1 Biological Polysiloxanes PBK, B2M, CD79B TAAR1 3041/4885KMT2A 1152/4885DAO 941/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.