⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL166316 | 0.82 | — | — | |
| SCHEMBL30166533 | 0.82 | — | — | |
| SCHEMBL14393839 | 0.79 | — | — | |
| SCHEMBL20043 | 0.78 | HTT (0.50) | — | |
| SCHEMBL29546988 | 0.78 | HTT (0.50) | — | |
| SCHEMBL1043688 | 0.77 | — | — | |
| SCHEMBL31133690 | 0.76 | HTT (0.48) | — | |
| SCHEMBL28162273 | 0.75 | CYP1A2 (0.45) | — | |
| SCHEMBL4135652 | 0.74 | GAA (0.43) | — | |
| SCHEMBL21722106 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 120 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3484865-B1 | SOMATOSTATIN MODULATORS AND USES THEREOF | CRINETICS PHARMACEUTICALS INC (US) | 2022-09-14 | — | — | EP | claimed |
| EP-2529388-B1 | FRAGMENTATION REAGENTS FOR MASS SPECTROMETRY | MICROMASS LTD (GB) | 2019-10-23 | — | — | EP | claimed |
| US-20130122599-A1 | Fragmentation Reagents For Mass Spectrometry | MICROMASS UK LIMITED (GB) | 2013-05-16 | — | — | US | claimed |
| EP-2529388-A1 | FRAGMENTATION REAGENTS FOR MASS SPECTROMETRY | Micromass UK Limited (GB) | 2012-12-05 | — | — | EP | claimed |
| WO-2011092515-A1 | FRAGMENTATION REAGENTS FOR MASS SPECTROMETRY | MICROMASS UK LIMITED (GB) | 2011-08-04 | — | — | WO | claimed |
| EP-1222188-A1 | NOVEL IMIDAZOPYRIDINE CARBONITRILE COMPOUNDS | AstraZeneca AB (SE) | 2002-07-17 | — | — | EP | claimed |
| WO-2001025237-A1 | NOVEL IMIDAZOPYRIDINE CARBONITRILE COMPOUNDS | ASTRAZENECA AB (SE) | 2001-04-12 | — | — | WO | claimed |
| US-5480995-A | Process for the preparation of 6-amino-nicotinonitriles | BAYER AKTIENGESELLSCHAFT (DE) | 1996-01-02 | — | — | US | claimed |
| EP-0057827-B1 | PROCESS FOR THE PREPARATION OF 2-AMINOPYRIDINE DERIVATIVES | BASF Aktiengesellschaft (DE) | 1986-08-13 | — | — | EP | claimed |
| US-4395555-A | Preparation of 2-aminopyridine derivatives | BASF AKTIENGESELLSCHAFT (DE) | 1983-07-26 | — | — | US | claimed |
| EP-4719394-A2 | INHIBITORS OF TYK2 | Atomwise Inc. (US) | 2026-04-08 | — | — | EP | disclosed |
| US-20260048051-A1 | TREATMENT OF INFLAMMATORY BOWEL DISEASE | ATOMWISE INC (US) | 2026-02-19 | — | — | US | disclosed |
| US-12358904-B2 | Inhibitors of TYK2 | Atomwise Inc. (US) | 2025-07-15 | — | — | US | disclosed |
| US-20240425484-A1 | INHIBITORS OF TYK2 | Atomwise Inc. | 2024-12-26 | — | — | US | disclosed |
| US-20240417396-A1 | INHIBITORS OF TYK2 | Atomwise Inc. | 2024-12-19 | — | — | US | disclosed |
| US-4567186-A | 5-Heteryl-1,6-naphthyridin-2(1H)-ones, cardiotonic use thereof and intermediates therefor | STERLING DRUG INC. (US) | 1986-01-28 | — | — | US | disclosed |
| US-4410465-A | Preparation of butadiene dinitriles | BASF AKTIENGESELLSCHAFT (DE) | 1983-10-18 | — | — | US | disclosed |
| US-4395555-A | Preparation of 2-aminopyridine derivatives | BASF AKTIENGESELLSCHAFT (DE) | 1983-07-26 | — | — | US | disclosed |
| US-4395555-A | Preparation of 2-aminopyridine derivatives | BASF AKTIENGESELLSCHAFT (DE) | 1983-07-26 | — | — | US | disclosed |
| EP-0046446-A1 | Polyazaheterocyclic compounds, process for their preparation and pharmaceutical compositions containing them | CIBA-GEIGY AG (CH) | 1982-02-24 | — | — | EP | disclosed |