Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC29A1 | Q99808 | 6/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 7/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 6/20 | 0.37 |
| ▸ | ADORA2B | P29275 | 5/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.36 |
| ▸ | HINT1 | P49773 | 1/20 | 0.35 |
| ▸ | NT5E | P21589 | 1/20 | 0.33 |
| ▸ | PGK1 | P00558 | 1/20 | 0.33 |
| ▸ | PGK2 | P07205 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15070700 | 0.80 | SLC29A1 (0.39) | SLC29A1ADORA3ADORA1ADORA2BADORA2A | |
| SCHEMBL22241451 | 0.79 | SLC29A1 (0.35) | SLC29A1ADORA3ADORA1ADORA2BADORA2A | |
| SCHEMBL20879526 | 0.76 | STING1 (0.45) | ADORA3HINT1NT5E | |
| SCHEMBL21063965 | 0.76 | SLC29A1 (0.35) | SLC29A1ADORA3ADORA1ADORA2BADORA2A | |
| SCHEMBL15255196 | 0.75 | SLC29A1 (0.41) | SLC29A1ADORA3ADORA1ADORA2BADORA2A | |
| SCHEMBL21063966 | 0.74 | SLC29A1 (0.40) | SLC29A1ADORA3ADORA1ADORA2BADORA2A | |
| SCHEMBL18656236 | 0.73 | ADORA2A (0.46) | SLC29A1ADORA3ADORA1ADORA2BADORA2A | |
| SCHEMBL18877363 | 0.72 | ADORA2A (0.39) | SLC29A1ADORA3ADORA1ADORA2BADORA2A | |
| SCHEMBL8970907 | 0.72 | ADORA2A (0.62) | SLC29A1ADORA3ADORA1ADORA2BADORA2A | |
| SCHEMBL8970895 | 0.72 | ADORA2A (0.62) | SLC29A1ADORA3ADORA1ADORA2BADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3013340-B1 | SUBSTITUTED NUCLEOSIDES, NUCLEOTIDES AND ANALOGS THEREOF | JANSSEN BIOPHARMA INC (US) | 2023-06-07 | — | — | EP | disclosed |
| US-RE48171-E1 | Substituted nucleosides, nucleotides and analogs thereof | Janssen Biopharma, Inc. (US) | 2020-08-25 | — | — | US | disclosed |