Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 4/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | EED | O75530 | 1/20 | 0.45 |
| ▸ | KDM1A | O60341 | 10/20 | 0.42 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.41 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.41 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.41 |
| ▸ | RCOR1 | Q9UKL0 | 5/20 | 0.41 |
| ▸ | MAOA | P21397 | 2/20 | 0.41 |
| ▸ | KDM1B | Q8NB78 | 2/20 | 0.41 |
| ▸ | HTR3A | P46098 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22365339 | 0.94 | EED (0.54) | SLC6A2SLC6A4SLC6A3EED | |
| SCHEMBL22365416 | 0.93 | SLC6A2 (0.48) | SLC6A2SLC6A4SLC6A3KDM1ATPSAB1 | |
| SCHEMBL22365401 | 0.91 | GLA (0.45) | EED | |
| SCHEMBL22365414 | 0.89 | EED (0.43) | SLC6A2SLC6A4SLC6A3EEDTPSAB1 | |
| SCHEMBL3929685 | 0.87 | KDM5A (0.48) | — | |
| SCHEMBL22365429 | 0.82 | HRH1 (0.50) | EED | |
| SCHEMBL22365312 | 0.82 | ACACB (0.44) | SLC6A4 | |
| SCHEMBL22365317 | 0.81 | SLC6A2 (0.48) | SLC6A2SLC6A4SLC6A3EEDKDM1A | |
| SCHEMBL17277590 | 0.80 | SLC6A2 (0.60) | SLC6A2SLC6A4SLC6A3EEDKDM1A | |
| SCHEMBL12075488 | 0.80 | SLC6A2 (0.60) | SLC6A2SLC6A4SLC6A3EEDKDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3102198-B1 | ANTIDIABETIC COMPOUNDS | MERCK SHARP & DOHME (US) | 2020-08-26 | — | — | EP | disclosed |