Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR5 | Q9H228 | 11/20 | 0.53 |
| ▸ | HRH2 | P25021 | 6/20 | 0.50 |
| ▸ | HRH1 | P35367 | 6/20 | 0.50 |
| ▸ | S1PR1 | P21453 | 6/20 | 0.47 |
| ▸ | S1PR3 | Q99500 | 4/20 | 0.47 |
| ▸ | DPP4 | P27487 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16343181 | 1.00 | S1PR5 (0.53) | S1PR5HRH2HRH1S1PR1S1PR3 | |
| SCHEMBL16294380 | 1.00 | S1PR5 (0.53) | S1PR5HRH2HRH1S1PR1S1PR3 | |
| SCHEMBL16306055 | 0.93 | S1PR5 (0.52) | S1PR5HRH2HRH1S1PR1S1PR3 | |
| SCHEMBL17968906 | 0.93 | S1PR5 (0.52) | S1PR5HRH2HRH1S1PR1S1PR3 | |
| SCHEMBL16375230 | 0.92 | HRH2 (0.47) | S1PR5HRH2HRH1S1PR1S1PR3 | |
| SCHEMBL16305723 | 0.91 | S1PR5 (0.49) | S1PR5HRH2HRH1S1PR1S1PR3 | |
| SCHEMBL20900665 | 0.89 | S1PR5 (0.51) | S1PR5HRH2HRH1S1PR1S1PR3 | |
| SCHEMBL20426686 | 0.89 | S1PR5 (0.51) | S1PR5HRH2HRH1S1PR1S1PR3 | |
| SCHEMBL20427358 | 0.89 | S1PR5 (0.51) | S1PR5HRH2HRH1S1PR1S1PR3 | |
| SCHEMBL19517709 | 0.88 | HRH2 (0.41) | S1PR5HRH2HRH1S1PR1DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3230276-B1 | GLP-1 RECEPTOR MODULATORS | CELGENE INT II SARL (CH) | 2020-09-02 | — | — | EP | disclosed |