Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 20/20 | 0.75 |
| ▸ | TLR7 | Q9NYK1 | 8/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19940724 | 0.90 | TLR8 (0.75) | TLR8TLR7 | |
| SCHEMBL19940930 | 0.90 | TLR8 (0.75) | TLR8TLR7 | |
| SCHEMBL18109696 | 0.89 | TLR8 (0.74) | TLR8TLR7 | |
| SCHEMBL18109697 | 0.89 | TLR8 (0.74) | TLR8TLR7 | |
| SCHEMBL18125210 | 0.86 | TLR8 (0.74) | TLR8TLR7 | |
| SCHEMBL18125191 | 0.86 | TLR8 (0.74) | TLR8TLR7 | |
| SCHEMBL18124808 | 0.85 | TLR8 (1.00) | TLR8TLR7 | |
| SCHEMBL18124742 | 0.85 | TLR8 (1.00) | TLR8TLR7 | |
| SCHEMBL19940905 | 0.82 | TLR8 (0.73) | TLR8TLR7 | |
| SCHEMBL19940723 | 0.82 | TLR8 (0.73) | TLR8TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3507288-B1 | 4,6-DIAMINO-PYRIDO[3,2-D]PYRIMIDINE DERIVATIES AS TOLL LIKE RECEPTOR MODULATORS | GILEAD SCIENCES INC (US) | 2020-08-26 | — | — | EP | disclosed |