Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CREBBP | Q92793 | 6/20 | 0.38 |
| ▸ | BRD4 | O60885 | 4/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22368908 | 0.95 | CREBBP (0.41) | CREBBPBRD4 | |
| SCHEMBL22368867 | 0.86 | CREBBP (0.42) | CREBBPBRD4 | |
| SCHEMBL22368983 | 0.84 | CREBBP (0.34) | CREBBPBRD4 | |
| SCHEMBL22369179 | 0.84 | BRD4 (0.31) | CREBBPBRD4 | |
| SCHEMBL22368975 | 0.83 | CREBBP (0.40) | CREBBPBRD4 | |
| SCHEMBL22369176 | 0.79 | CREBBP (0.36) | CREBBPBRD4 | |
| SCHEMBL22368981 | 0.79 | CREBBP (0.37) | CREBBPBRD4 | |
| SCHEMBL22368907 | 0.78 | BRD4 (0.35) | CREBBPBRD4 | |
| SCHEMBL22368846 | 0.76 | BRD4 (0.39) | CREBBPBRD4 | |
| SCHEMBL17680934 | 0.72 | CREBBP (0.71) | CREBBPBRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3204360-B1 | THERAPEUTIC COMPOUNDS AND USES THEREOF | GENENTECH INC (US) | 2020-08-26 | — | — | EP | disclosed |