Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CREBBP | Q92793 | 20/20 | 0.78 |
| ▸ | BRD4 | O60885 | 4/20 | 0.78 |
| ▸ | EP300 | Q09472 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19518299 | 0.88 | CREBBP (1.00) | CREBBPBRD4 | |
| SCHEMBL17673295 | 0.88 | CREBBP (1.00) | CREBBPBRD4 | |
| SCHEMBL22369039 | 0.84 | CREBBP (0.60) | CREBBPBRD4EP300 | |
| SCHEMBL24316555 | 0.80 | CREBBP (0.62) | CREBBPBRD4 | |
| SCHEMBL22368790 | 0.79 | CREBBP (0.53) | CREBBPBRD4EP300 | |
| SCHEMBL22369070 | 0.78 | CREBBP (0.70) | CREBBPBRD4EP300 | |
| SCHEMBL17794572 | 0.77 | CREBBP (0.59) | CREBBPBRD4EP300 | |
| SCHEMBL22369240 | 0.76 | CREBBP (0.60) | CREBBPBRD4EP300 | |
| SCHEMBL22368824 | 0.76 | CREBBP (0.54) | CREBBPBRD4 | |
| SCHEMBL19368895 | 0.76 | CREBBP (0.58) | CREBBPBRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3204360-B1 | THERAPEUTIC COMPOUNDS AND USES THEREOF | GENENTECH INC (US) | 2020-08-26 | — | — | EP | disclosed |