Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 2/20 | 0.45 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | LIN28A | Q9H9Z2 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20882972 | 0.85 | MAPT (0.47) | NR1H2NR1H3MEN1KMT2ANPSR1 | |
| SCHEMBL18157965 | 0.84 | GAA (0.39) | NR1H2NR1H3ALDH1A1MEN1KMT2A | |
| SCHEMBL20882978 | 0.81 | TDP1 (0.46) | NR1H2NR1H3MEN1KMT2ANPSR1 | |
| SCHEMBL20882988 | 0.80 | SMN1; SMN2 (0.42) | NR1H2NR1H3ALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL14921039 | 0.79 | CYP2C19 (0.50) | NR1H2NR1H3ALDH1A1MEN1KMT2A | |
| SCHEMBL16000559 | 0.76 | NR1H2 (0.59) | NR1H2NR1H3ALDH1A1MEN1KMT2A | |
| SCHEMBL5049849 | 0.72 | ESR1 (0.45) | NR1H2NR1H3MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL26112722 | 0.72 | CYP2D6 (0.55) | NR1H2NR1H3ALDH1A1MEN1KMT2A | |
| SCHEMBL18695436 | 0.71 | GAA (0.47) | ALDH1A1MEN1KMT2ANPSR1POLB | |
| SCHEMBL8179853 | 0.71 | MAPT (0.45) | NR1H2NR1H3KMT2ANPSR1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200270218-A1 | SENSORS FOR DETECTION OF NEGATIVELY CHARGED PHOSPHATE-CONTAINING MEMBRANES AND MEMBRANE COMPONENTS | THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO (CA) | 2020-08-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200270218-A1 | SENSORS FOR DETECTION OF NEGATIVELY CHARGED PHOSPHATE-CONTAINING MEMBRANES AND MEMBRANE COMPONENTS | PHOSPHO1, PTEN, INPPL1 | NR1H2 3695/4885NR1H3 3809/4885ALDH1A1 4871/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.