Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | CASP1 | P29466 | 1/20 | 0.50 |
| ▸ | CASP7 | P55210 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | ABL1 | P00519 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA7 | P43166 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.44 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.44 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19674267 | 0.84 | SMN1; SMN2 (0.47) | KDM4EMAPTALDH1A1HSD17B10GAA | |
| SCHEMBL27762519 | 0.84 | SMN1; SMN2 (0.47) | KDM4EMAPTALDH1A1HSD17B10GAA | |
| SCHEMBL15154757 | 0.81 | NPC1 (0.58) | KDM4EMAPTALDH1A1HSD17B10TDP1 | |
| SCHEMBL5327455 | 0.81 | SMN1; SMN2 (0.71) | KDM4EALDH1A1HSD17B10HPGDCASP1 | |
| SCHEMBL28776120 | 0.81 | SMN1; SMN2 (0.45) | KDM4EMAPTALDH1A1HSD17B10GAA | |
| SCHEMBL4157373 | 0.81 | MAPT (0.53) | KDM4EMAPTALDH1A1HSD17B10GAA | |
| SCHEMBL1839092 | 0.81 | KDM4E (0.54) | KDM4EMAPTALDH1A1HSD17B10GAA | |
| Hydrochloric Acid SCHEMBL2176205 | 0.80 | NPC1 (0.56) | KDM4EMAPTALDH1A1HSD17B10SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL17825653 | 0.79 | MAPT (0.51) | KDM4EMAPTALDH1A1HSD17B10GAA | |
| Hydrochloric Acid SCHEMBL1403100 | 0.79 | KDM4E (0.53) | KDM4EMAPTALDH1A1HSD17B10GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2374791-A1 | Insecticidal 4-phenyl-1H pyrazoles | Bayer CropScience Aktiengesellschaft (DE) | 2011-10-12 | — | — | EP | disclosed |
| US-20110190365-A1 | Insecticidal 4-phenyl-1H-pyrazoles | BAYER CROP SCIENCE AG (DE) | 2011-08-04 | — | — | US | disclosed |
| US-20110190365-A1 | Insecticidal 4-phenyl-1H-pyrazoles | BAYER CROP SCIENCE AG (DE) | 2011-08-04 | — | — | US | disclosed |
| US-20110190365-A1 | Insecticidal 4-phenyl-1H-pyrazoles | BAYER CROP SCIENCE AG (DE) | 2011-08-04 | — | — | US | disclosed |
| WO-2010017902-A1 | INSECTICIDAL 4-PHENYL-1H-PYRAZOLES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2010-02-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110190365-A1 | Insecticidal 4-phenyl-1H-pyrazoles | CYP4X1, CYP4B1, CYP3A4 | KDM4E 821/4885MAPT 2483/4885ALDH1A1 1129/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.