Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | PRCP | P42785 | 2/20 | 0.44 |
| ▸ | NOS2 | P35228 | 2/20 | 0.42 |
| ▸ | NOS3 | P29474 | 1/20 | 0.42 |
| ▸ | NOS1 | P29475 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.39 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.39 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL708271 | 0.98 | — | — | |
| SCHEMBL51793 | 0.98 | — | — | |
| SCHEMBL118100 | 0.98 | — | — | |
| Ammonia Solution, Strong SCHEMBL16464378 | 0.96 | CYP3A4 (0.44) | CYP3A4CYP2D6CYP1A2CYP2C19PRCP | |
| Methane SCHEMBL28919172 | 0.96 | CYP3A4 (0.44) | CYP3A4CYP2D6CYP1A2CYP2C19PRCP | |
| Water SCHEMBL16400402 | 0.96 | CYP3A4 (0.44) | CYP3A4CYP2D6CYP1A2CYP2C19PRCP | |
| Hydrochloric Acid SCHEMBL27762272 | 0.96 | CYP3A4 (0.44) | CYP3A4CYP2D6CYP1A2CYP2C19PRCP | |
| Hydrochloric Acid SCHEMBL190501 | 0.96 | CYP3A4 (0.44) | CYP3A4CYP2D6CYP1A2CYP2C19PRCP | |
| Hydrochloric Acid SCHEMBL51792 | 0.96 | CYP3A4 (0.44) | CYP3A4CYP2D6CYP1A2CYP2C19PRCP | |
| Hydrochloric Acid SCHEMBL1223341 | 0.96 | CYP3A4 (0.44) | CYP3A4CYP2D6CYP1A2CYP2C19PRCP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2536500-A1 | SUPPORTED METAL CATALYSTS | Johnson Matthey PLC (GB) | 2012-12-26 | — | — | EP | disclosed |
| WO-2011101679-A1 | SUPPORTED METAL CATALYSTS | JOHNSON MATTHEY PLC (GB) | 2011-08-25 | — | — | WO | disclosed |