SCHEMBL2238049

SCHEMBL2238049

C#CC(O)Br

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bicarbonate SCHEMBL5865890 0.86
Carbamic Acid SCHEMBL5865959 0.80
SCHEMBL597762 0.76
SCHEMBL830324 0.70
SCHEMBL270616 0.70
SCHEMBL5048999 0.67
SCHEMBL1077449 0.67
Bicarbonate SCHEMBL19712682 0.65
SCHEMBL4226099 0.64
SCHEMBL77308 0.64

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7078049-B2 Ultrafine emulsion containing a haloalkynyl derivative L'OREAL (FR) 2006-07-18 US claimed
US-20030073689-A1 Ultrafine emulsion containing a haloalkynyl derivative L'OREAL (FR) 2003-04-17 US claimed
US-20120122816-A1 COMPOSITIONS AND METHODS FOR ORGAN PRESERVATION RESOLVYX PHARMACEUTICALS, INC. (US) 2012-05-17 US disclosed
US-20110245528-A1 THERAPEUTIC COMPOUNDS SCHWARTZ C ERIC 2011-10-06 US disclosed
US-20110190242-A1 COMPOSITIONS AND METHODS FOR THE TREATMENT OF INFLAMMATORY DISEASE RESOLVYX PHARMACEUTICALS, INC. (US) 2011-08-04 US disclosed
WO-2010091226-A1 COMPOSITIONS AND METHODS FOR ORGAN PRESERVATION RESOLVYX PHARMACEUTICALS, INC. (US) 2010-08-12 WO disclosed
WO-2010039531-A1 THERAPEUTIC COMPOUNDS RESOLVYX PHARMACEUTICALS, INC. (US) 2010-04-08 WO disclosed
WO-2010039529-A2 COMPOSITIONS AND METHODS FOR THE TREAMENT OF INFLAMMATORY DISEASE RESOLVYX PHARMACEUTICALS, INC. (US) 2010-04-08 WO disclosed
US-20020155443-A1 Metal binding DNA interactive compounds BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM 2002-10-24 US disclosed
CN-1111616-A Bromopropargyl quaternary ammonium compounds having antimicrobial activity ROHM & HAAS (US) 1995-11-15 CN disclosed
EP-0675117-A1 Bromopropargyl quaternary ammonium compounds having antimicrobial activity ROHM AND HAAS COMPANY (US) 1995-10-04 EP disclosed
US-5411933-A Bromopropargyl quarternary ammonium compounds having antimicrobial activity ROHM & HAAS COMPANY (US) 1995-05-02 US disclosed
US-4592865-A Antibiotic SHIONOGI & CO., LTD. (JP) 1986-06-03 US disclosed