Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 8/20 | 0.61 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.61 |
| ▸ | KDR | P35968 | 5/20 | 0.54 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.52 |
| ▸ | TNNI3K | Q59H18 | 2/20 | 0.52 |
| ▸ | PLK4 | O00444 | 1/20 | 0.52 |
| ▸ | AURKA | O14965 | 1/20 | 0.52 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.52 |
| ▸ | JAK2 | O60674 | 1/20 | 0.52 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.52 |
| ▸ | ABL1 | P00519 | 1/20 | 0.52 |
| ▸ | LCK | P06239 | 1/20 | 0.52 |
| ▸ | FYN | P06241 | 1/20 | 0.52 |
| ▸ | LYN | P07948 | 1/20 | 0.52 |
| ▸ | RET | P07949 | 1/20 | 0.52 |
| ▸ | ROS1 | P08922 | 1/20 | 0.52 |
| ▸ | SRC | P12931 | 1/20 | 0.52 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.52 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.52 |
| ▸ | TYK2 | P29597 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2240532 | 0.88 | KDR (0.54) | TLR8TLR7KDRMAPK14TNNI3K | |
| SCHEMBL4022786 | 0.82 | PDGFRB (0.51) | TLR8TLR7KDRMAPK14TNNI3K | |
| SCHEMBL14284697 | 0.82 | TLR8 (0.58) | TLR8TLR7KDRMAPK14TNNI3K | |
| SCHEMBL2355329 | 0.82 | KDR (0.52) | TLR8TLR7KDRMAPK14TNNI3K | |
| SCHEMBL2243448 | 0.81 | KDR (0.66) | TLR8TLR7KDRMAPK14TNNI3K | |
| SCHEMBL5583621 | 0.81 | TLR7 (0.57) | TLR8TLR7KDRMAPK14TNNI3K | |
| SCHEMBL14284392 | 0.81 | KDR (0.60) | TLR8TLR7KDRMAPK14TNNI3K | |
| SCHEMBL2237399 | 0.80 | TLR8 (0.51) | TLR8TLR7KDRMAPK14TNNI3K | |
| SCHEMBL5583862 | 0.79 | KDR (0.55) | TLR8TLR7KDRMAPK14TNNI3K | |
| SCHEMBL14284636 | 0.78 | KDR (0.55) | TLR8TLR7KDRMAPK14TNNI3K |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8003799-B2 | For agriculture | BAYER SAS (FR) | 2011-08-23 | — | — | US | disclosed |
| EP-1244627-B1 | PICOLINIC ACID DERIVATIVES AND THEIR USE AS FUNGICIDES | BAYER CROPSCIENCE SA (FR) | 2006-09-20 | — | — | EP | disclosed |
| US-20030191113-A1 | Picolinic acid derivatives and their use as fungicides | BAYER SAS (FR) | 2003-10-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030191113-A1 | Picolinic acid derivatives and their use as fungicides | PTPRG, CNPY2, CYP4X1 | TLR8 4466/4885TLR7 3498/4885KDR 4768/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.