Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 2/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15180381 | 0.93 | POLB (0.43) | TDP1POLBAPEX1HTTELANE | |
| SCHEMBL16559864 | 0.93 | POLB (0.43) | TDP1POLBAPEX1HTTELANE | |
| SCHEMBL16559814 | 0.91 | POLB (0.43) | TDP1POLBAPEX1HTTELANE | |
| SCHEMBL21102080 | 0.91 | POLB (0.43) | TDP1POLBAPEX1HTTELANE | |
| SCHEMBL16559835 | 0.91 | POLB (0.43) | TDP1POLBAPEX1HTTELANE | |
| SCHEMBL16559847 | 0.91 | POLB (0.43) | TDP1POLBAPEX1HTTELANE | |
| SCHEMBL26167221 | 0.90 | POLB (0.41) | TDP1POLBAPEX1HTTELANE | |
| SCHEMBL24180754 | 0.89 | POLB (0.40) | TDP1POLBAPEX1HTTELANE | |
| SCHEMBL17547075 | 0.89 | ELANE (0.41) | TDP1POLBAPEX1HTTELANE | |
| SCHEMBL18440992 | 0.89 | POLB (0.40) | TDP1POLBAPEX1HTTELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3248060-B1 | LIGHT MODULATION ELEMENT | MERCK PATENT GMBH (DE) | 2020-09-02 | — | — | EP | disclosed |