Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 11/20 | 0.86 |
| ▸ | SRC | P12931 | 6/20 | 0.86 |
| ▸ | KDR | P35968 | 6/20 | 0.86 |
| ▸ | FLT4 | P35916 | 2/20 | 0.86 |
| ▸ | RET | P07949 | 2/20 | 0.86 |
| ▸ | BRAF | P15056 | 2/20 | 0.86 |
| ▸ | EPHB4 | P54760 | 2/20 | 0.86 |
| ▸ | CIT | O14578 | 1/20 | 0.86 |
| ▸ | GAK | O14976 | 1/20 | 0.86 |
| ▸ | EPHB6 | O15197 | 1/20 | 0.86 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.86 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.86 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.86 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.86 |
| ▸ | RPS6KA4 | O75676 | 1/20 | 0.86 |
| ▸ | STK17B | O94768 | 1/20 | 0.86 |
| ▸ | STK10 | O94804 | 1/20 | 0.86 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.86 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.86 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.86 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11304 | 0.95 | EGFR (0.86) | EGFRSRCKDRFLT4RET | |
| SCHEMBL30416288 | 0.95 | EGFR (0.86) | EGFRSRCKDRFLT4RET | |
| SCHEMBL799681 | 0.93 | EGFR (0.83) | EGFRSRCKDRFLT4RET | |
| SCHEMBL1734701 | 0.92 | EGFR (1.00) | EGFRSRCKDRFLT4RET | |
| SCHEMBL22667930 | 0.92 | EGFR (0.82) | EGFRSRCKDRFLT4RET | |
| Gefitinib SCHEMBL29351046 | 0.92 | EGFR (1.00) | EGFRSRCKDRFLT4RET | |
| Gefitinib SCHEMBL7866 | 0.92 | EGFR (1.00) | EGFRSRCKDRFLT4RET | |
| Gefitinib SCHEMBL29351336 | 0.92 | EGFR (1.00) | EGFRSRCKDRFLT4RET | |
| Gefitinib SCHEMBL465143 | 0.92 | EGFR (1.00) | EGFRSRCKDRFLT4RET | |
| Gefitinib SCHEMBL2770155 | 0.92 | EGFR (0.98) | EGFRSRCKDRFLT4RET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3702783-A1 | METHODS FOR DETERMINING CELLS SUCH AS CIRCULATING CANCER OR FETAL CELLS | Analiza, Inc. (US) | 2020-09-02 | — | — | EP | disclosed |