Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH2 | P25021 | 10/20 | 0.46 |
| ▸ | HRH1 | P35367 | 10/20 | 0.46 |
| ▸ | RARB | P10826 | 1/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.37 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | AKT1 | P31749 | 1/20 | 0.36 |
| ▸ | AKT2 | P31751 | 1/20 | 0.36 |
| ▸ | AKT3 | Q9Y243 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PPARD | Q03181 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 2/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17834712 | 1.00 | HRH2 (0.46) | HRH2HRH1RARBS1PR1S1PR5 | |
| Acetic Acid SCHEMBL17968875 | 0.98 | HRH2 (0.47) | HRH2HRH1RARBS1PR1S1PR5 | |
| Acetic Acid SCHEMBL17968877 | 0.98 | HRH2 (0.47) | HRH2HRH1RARBS1PR1S1PR5 | |
| SCHEMBL17834713 | 0.91 | HRH2 (0.49) | HRH2HRH1RARBS1PR1S1PR5 | |
| SCHEMBL16294794 | 0.91 | HRH2 (0.46) | HRH2HRH1RARBS1PR1S1PR5 | |
| SCHEMBL16294793 | 0.91 | HRH2 (0.46) | HRH2HRH1RARBS1PR1S1PR5 | |
| Hydrochloric Acid SCHEMBL17825544 | 0.90 | HRH2 (0.49) | HRH2HRH1RARBS1PR1S1PR5 | |
| Hydrochloric Acid SCHEMBL17968764 | 0.90 | HRH2 (0.49) | HRH2HRH1RARBS1PR1S1PR5 | |
| Acetic Acid SCHEMBL17968916 | 0.90 | HRH2 (0.49) | HRH2HRH1RARBS1PR1S1PR5 | |
| Acetic Acid SCHEMBL17968915 | 0.90 | HRH2 (0.49) | HRH2HRH1RARBS1PR1S1PR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3230276-B1 | GLP-1 RECEPTOR MODULATORS | CELGENE INT II SARL (CH) | 2020-09-02 | — | — | EP | disclosed |