Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | LY96 | Q9Y6Y9 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.39 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15037038 | 0.92 | MAPT (0.43) | MAPTTDP1POLBLY96NPSR1 | |
| SCHEMBL17825520 | 0.92 | MAPT (0.43) | MAPTTDP1POLBLY96NPSR1 | |
| SCHEMBL17825497 | 0.92 | MAPT (0.43) | MAPTTDP1POLBLY96NPSR1 | |
| SCHEMBL22384066 | 0.89 | LY96 (0.46) | MAPTTDP1POLBLY96NPSR1 | |
| SCHEMBL15037031 | 0.89 | LY96 (0.46) | MAPTTDP1POLBLY96NPSR1 | |
| SCHEMBL15096428 | 0.84 | ITGB1 (0.41) | MAPTTDP1POLB | |
| SCHEMBL19533184 | 0.84 | LY96 (0.48) | MAPTTDP1POLBLY96 | |
| SCHEMBL22384075 | 0.84 | MAPT (0.37) | MAPTTDP1POLBLY96NPSR1 | |
| SCHEMBL17834723 | 0.84 | LY96 (0.40) | MAPTTDP1POLBLY96NPSR1 | |
| SCHEMBL22384234 | 0.84 | LY96 (0.40) | MAPTTDP1POLBLY96NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3230276-B1 | GLP-1 RECEPTOR MODULATORS | CELGENE INT II SARL (CH) | 2020-09-02 | — | — | EP | disclosed |