Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 1/20 | 0.46 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.43 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.43 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.43 |
| ▸ | CBX4 | O00257 | 3/20 | 0.43 |
| ▸ | CBX7 | O95931 | 3/20 | 0.43 |
| ▸ | CDYL2 | Q8N8U2 | 3/20 | 0.43 |
| ▸ | CBX8 | Q9HC52 | 3/20 | 0.43 |
| ▸ | PPARG | P37231 | 2/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CBX6 | O95503 | 1/20 | 0.39 |
| ▸ | CBX2 | Q14781 | 1/20 | 0.39 |
| ▸ | ITGB1 | P05556 | 3/20 | 0.39 |
| ▸ | ITGAV | P06756 | 1/20 | 0.39 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.39 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.39 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | CTSB | P07858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16305840 | 1.00 | RARB (0.46) | RARBITGB3ITGA2BKLKB1CBX4 | |
| SCHEMBL16305736 | 0.98 | KLKB1 (0.43) | RARBITGB3ITGA2BKLKB1CBX4 | |
| SCHEMBL16305950 | 0.93 | PPARG (0.48) | RARBITGB3ITGA2BKLKB1CBX4 | |
| SCHEMBL16305949 | 0.93 | KLKB1 (0.46) | ITGB3ITGA2BKLKB1CBX4CBX7 | |
| SCHEMBL16295654 | 0.92 | PPARG (0.50) | RARBITGB3ITGA2BKLKB1CBX4 | |
| SCHEMBL16305364 | 0.92 | PPARG (0.50) | RARBITGB3ITGA2BKLKB1CBX4 | |
| SCHEMBL16306232 | 0.92 | PPARG (0.50) | RARBITGB3ITGA2BKLKB1CBX4 | |
| SCHEMBL16305360 | 0.92 | PPARG (0.50) | RARBITGB3ITGA2BKLKB1CBX4 | |
| SCHEMBL16305951 | 0.92 | PPARG (0.50) | RARBITGB3ITGA2BKLKB1CBX4 | |
| SCHEMBL16295701 | 0.92 | PPARG (0.50) | RARBITGB3ITGA2BKLKB1CBX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3230276-B1 | GLP-1 RECEPTOR MODULATORS | CELGENE INT II SARL (CH) | 2020-09-02 | — | — | EP | disclosed |