Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR5 | Q9H228 | 10/20 | 0.46 |
| ▸ | PPARG | P37231 | 3/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 6/20 | 0.41 |
| ▸ | S1PR3 | Q99500 | 4/20 | 0.41 |
| ▸ | HRH2 | P25021 | 5/20 | 0.40 |
| ▸ | HRH1 | P35367 | 5/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16380250 | 1.00 | S1PR5 (0.46) | S1PR5PPARGPPARAS1PR1S1PR3 | |
| SCHEMBL16305728 | 0.94 | S1PR5 (0.47) | S1PR5PPARGPPARAS1PR1S1PR3 | |
| SCHEMBL17834831 | 0.94 | S1PR5 (0.49) | S1PR5PPARGPPARAS1PR1S1PR3 | |
| SCHEMBL17834464 | 0.94 | S1PR5 (0.45) | S1PR5PPARGPPARAS1PR1S1PR3 | |
| SCHEMBL16306062 | 0.94 | S1PR5 (0.48) | S1PR5PPARGPPARAS1PR1S1PR3 | |
| SCHEMBL16305732 | 0.94 | S1PR5 (0.48) | S1PR5PPARGPPARAS1PR1S1PR3 | |
| SCHEMBL16305976 | 0.93 | S1PR5 (0.46) | S1PR5PPARGPPARAS1PR1S1PR3 | |
| SCHEMBL16305731 | 0.93 | S1PR5 (0.47) | S1PR5PPARGPPARAS1PR1S1PR3 | |
| SCHEMBL16306006 | 0.93 | S1PR5 (0.47) | S1PR5PPARGPPARAS1PR1S1PR3 | |
| SCHEMBL16380249 | 0.93 | S1PR5 (0.47) | S1PR5PPARGPPARAS1PR1S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3230276-B1 | GLP-1 RECEPTOR MODULATORS | CELGENE INT II SARL (CH) | 2020-09-02 | — | — | EP | disclosed |