Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR5 | Q9H228 | 9/20 | 0.47 |
| ▸ | S1PR1 | P21453 | 6/20 | 0.47 |
| ▸ | S1PR3 | Q99500 | 4/20 | 0.47 |
| ▸ | PPARG | P37231 | 3/20 | 0.47 |
| ▸ | PPARA | Q07869 | 1/20 | 0.47 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.42 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.42 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.41 |
| ▸ | RARB | P10826 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17834752 | 1.00 | S1PR5 (0.47) | S1PR5S1PR1S1PR3PPARGPPARA | |
| SCHEMBL17834601 | 0.95 | S1PR5 (0.48) | S1PR5S1PR1S1PR3PPARGPPARA | |
| SCHEMBL17834718 | 0.95 | S1PR5 (0.47) | S1PR5S1PR1S1PR3PPARGPPARA | |
| SCHEMBL17995157 | 0.95 | S1PR5 (0.47) | S1PR5S1PR1S1PR3PPARGPPARA | |
| SCHEMBL16305728 | 0.94 | S1PR5 (0.47) | S1PR5S1PR1S1PR3PPARGPPARA | |
| SCHEMBL17834464 | 0.94 | S1PR5 (0.45) | S1PR5S1PR1S1PR3PPARGPPARA | |
| SCHEMBL17834443 | 0.94 | S1PR5 (0.47) | S1PR5S1PR1S1PR3PPARGPPARA | |
| SCHEMBL17834715 | 0.94 | S1PR5 (0.47) | S1PR5S1PR1S1PR3PPARGPPARA | |
| SCHEMBL17834748 | 0.94 | S1PR5 (0.47) | S1PR5S1PR1S1PR3PPARGPPARA | |
| SCHEMBL17834825 | 0.94 | S1PR1 (0.42) | S1PR5S1PR1S1PR3PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3230276-B1 | GLP-1 RECEPTOR MODULATORS | CELGENE INT II SARL (CH) | 2020-09-02 | — | — | EP | disclosed |