Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Vanillyl Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 known ✓ | P03956 | 1/20 | 0.62 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.62 |
| ▸ | TSHR | P16473 | 2/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.62 |
| ▸ | FOS | P01100 | 1/20 | 0.61 |
| ▸ | TTR | P02766 | 1/20 | 0.61 |
| ▸ | JUN | P05412 | 1/20 | 0.61 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.61 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.61 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | GLA | P06280 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.59 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | AR | P10275 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Vanillyl Alcohol SCHEMBL27774687 | 0.96 | TAAR1 (0.67) | TAAR1TSHRMAPK1CYP3A4MMP1 | |
| Vanillyl Alcohol SCHEMBL29408335 | 0.96 | TAAR1 (0.67) | TAAR1TSHRMAPK1CYP3A4MMP1 | |
| Vanillyl Alcohol SCHEMBL62348 | 0.96 | TAAR1 (0.67) | TAAR1TSHRMAPK1CYP3A4MMP1 | |
| Vanillyl Alcohol SCHEMBL116860 | 0.94 | TAAR1 (0.65) | TAAR1TSHRMAPK1CYP3A4MMP1 | |
| Vanillyl Alcohol SCHEMBL579759 | 0.91 | TAAR1 (0.57) | TAAR1TSHRMAPK1CYP3A4MMP1 | |
| Alcohol SCHEMBL29288211 | 0.89 | TAAR1 (0.62) | TAAR1TSHRMAPK1CYP3A4MMP1 | |
| Vanillyl Alcohol SCHEMBL28896891 | 0.88 | TSHR (0.64) | TAAR1TSHRMAPK1CYP3A4MMP1 | |
| Vanillyl Alcohol SCHEMBL117923 | 0.88 | TAAR1 (0.54) | TAAR1TSHRMAPK1CYP3A4MMP1 | |
| Vanillyl Alcohol SCHEMBL29092590 | 0.87 | TAAR1 (0.57) | TAAR1TSHRMAPK1CYP3A4MMP1 | |
| Vanillyl Alcohol SCHEMBL19742906 | 0.87 | TSHR (0.58) | TAAR1TSHRMAPK1CYP3A4MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109553786-B | Vanillin cross-linked chitosan oligosaccharide mono-guanidine hydrochloride and microwave synthesis method thereof | 天津大学 | 2021-11-02 | — | — | CN | disclosed |
| CN-109575325-A | Vanillic aldehyde crosslinking chitosan oligosaccharide list guanidine hydrochloride is preparing the application in anti-oxidation medicine | 天津大学 | 2019-04-05 | — | — | CN | disclosed |
| CN-109553786-A | A kind of vanillic aldehyde crosslinking chitosan oligosaccharide list guanidine hydrochloride and its microwave synthesis method | 天津大学 | 2019-04-02 | — | — | CN | disclosed |
| CN-109549949-A | Vanillic aldehyde is crosslinked application of the chitosan oligosaccharide list guanidine hydrochloride in preparation treatment diabetes medicament | 天津大学 | 2019-04-02 | — | — | CN | disclosed |
| US-20170172184-A1 | Methods of Improving Production of Vanillin | EVOLVA SA (CH) | 2017-06-22 | — | — | US | disclosed |
| US-7981460-B2 | Substituted benzyl ester derivative and use thereof | AJINOMOTO CO., INC. (JP) | 2011-07-19 | — | — | US | disclosed |