Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 6/20 | 0.39 |
| ▸ | ESR1 | P03372 | 3/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | TYR | P14679 | 1/20 | 0.34 |
| ▸ | PTGES | O14684 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.32 |
| ▸ | MMP3 | P08254 | 1/20 | 0.32 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22386707 | 0.98 | PDK2 (0.39) | PDK2ESR1ESR2TP53MDM2 | |
| SCHEMBL22386769 | 0.94 | PDK2 (0.36) | PDK2ESR1ESR2TP53MDM2 | |
| SCHEMBL17804667 | 0.93 | MEN1 (0.37) | PDK2ESR1ESR2TP53MDM2 | |
| SCHEMBL16996134 | 0.92 | PDK2 (0.36) | PDK2ESR1ESR2TP53MDM2 | |
| SCHEMBL17854542 | 0.91 | KDM4E (0.37) | PDK2ESR1ESR2TP53MDM2 | |
| SCHEMBL16996423 | 0.91 | PDK2 (0.36) | PDK2ESR1ESR2TP53MDM2 | |
| SCHEMBL22211071 | 0.91 | PDK2 (0.42) | PDK2ESR1ESR2TP53LMNA | |
| SCHEMBL22211065 | 0.90 | PDK2 (0.41) | PDK2ESR1ESR2TP53LMNA | |
| SCHEMBL17804622 | 0.90 | MEN1 (0.40) | PDK2ESR1ESR2TP53MDM2 | |
| SCHEMBL17854527 | 0.89 | KDM4E (0.35) | PDK2ESR1ESR2TP53MDM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200280001-A1 | Polymer, Coating Composition Comprising Same, and Organic Light Emitting Diode Using Same | LG CHEM, LTD. (KR) | 2020-09-03 | — | — | US | disclosed |