SCHEMBL223886

SCHEMBL223886

CCCCSSCCCC

nearest known ligand 0.46

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.46
LMNA P02545 1/20 0.46
THRB P10828 1/20 0.43
NOS3 P29474 1/20 0.41
NOS1 P29475 1/20 0.41
NOS2 P35228 1/20 0.41
ALDH1A1 P00352 2/20 0.35
TDP1 Q9NUW8 1/20 0.35
DNM1 Q05193 6/20 0.33
SLC22A1 O15245 2/20 0.33
CES1 P23141 1/20 0.33
SLC22A2 O15244 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
USP2 O75604 1/20 0.32
ATM Q13315 1/20 0.32
HTT P42858 1/20 0.32
KMT2A Q03164 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11193512 1.00 TSHR (0.46) TSHRLMNATHRBNOS3NOS1
Water SCHEMBL27913545 0.96 TSHR (0.43) TSHRLMNATHRBNOS3NOS1
Ammonia Solution, Strong SCHEMBL28130901 0.96 TSHR (0.43) TSHRLMNATHRBNOS3NOS1
SCHEMBL28275329 0.96 TSHR (0.43) TSHRLMNATHRBNOS3NOS1
SCHEMBL10941694 0.96 TSHR (0.43) TSHRLMNATHRBNOS3NOS1
SCHEMBL27497457 0.96 TSHR (0.43) TSHRLMNATHRBNOS3NOS1
SCHEMBL3476016 0.96 TSHR (0.43) TSHRLMNATHRBNOS3NOS1
Water SCHEMBL28084836 0.96 TSHR (0.43) TSHRLMNATHRBNOS3NOS1
SCHEMBL10947396 0.96 TSHR (0.43) TSHRLMNATHRBNOS3NOS1
SCHEMBL3375811 0.93

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3181 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260083687-A1 COMPOUNDS FOR REDUCING LACTATION AND IMPROVING HEALTH AHV INT B V (NL) 2026-03-26 US claimed
US-12552997-B2 Targeted disulfide reduction in petroleum matrices CHEVRON U.S.A. INC. (US) 2026-02-17 US claimed
US-12525445-B2 Process solution for polymer processing DONGWOO FINE-CHEM CO., LTD. (KR) 2026-01-13 US claimed
EP-4611631-A2 METHOD AND DEVICE FOR DIAGNOSIS OF MEDICAL CONDITIONS Nanose Medical Ltd. (IL) 2025-09-10 EP claimed
EP-3874259-B1 CHEMICALLY SENSITIVE SENSOR COMPRISING MICRO-BARRIER AND METHOD OF FABRICATION THEREOF TECHNION RES & DEV FOUNDATION (IL) 2025-04-09 EP claimed
CN-119504848-A Preparation method of high-purity bis (2, 4-trimethylpentyl) phosphinic acid 上海电力大学 2025-02-25 CN claimed
EP-4507683-A1 COMPOUNDS FOR REDUCING LACTATION AND IMPROVING HEALTH AHV International B.V. (NL) 2025-02-19 EP claimed
US-12196699-B2 Chemically sensitive sensor comprising micro-barrier and method of fabrication thereof TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED (IL) 2025-01-14 US claimed
CN-117987022-B High-reflection material for color pavement and preparation thereof 浙江晨泽新材料科技有限公司 2024-11-05 CN claimed
WO-2024185762-A1 METHOD FOR PRODUCING POLYALKYLENE OXIDE-MODIFIED PHOSPHOLIPID 日油株式会社 2024-09-12 WO claimed
US-4488985-A STABILIZERS, ANTIOXIDANTS AKZONA INCORPORATED (US) 1984-12-18 US claimed
EP-0117883-A1 Preparation of 2-t-butyl-5-hydroxypyrimidine by hydrolysis of 2-t-butyl-5--bromo/chloropyrimidine THE DOW CHEMICAL COMPANY (US) 1984-09-12 EP claimed
US-4447447-A Composition, method of preparation thereof, method of application, apparatus for the control of larvae of the Gypsy Moth and other hardwood defoliators HRESCHAK BOHDAN O 1984-05-08 US claimed
US-4379930-A CATALYTIC HYDROLYSIS OF 2-T-BUTYL-5-PYRIMIDINE USING DIBUTYL DISULFIDE, ELEMENTAL SULFUR AND 2-PICOLINE-N-OXIDE AS CATALYST SYSTEM THE DOW CHEMICAL COMPANY (US) 1983-04-12 US claimed
EP-0070596-A1 Novel phosphor amidates containing a p-phenylene diamine group AKZO N.V. (NL) 1983-01-26 EP claimed
EP-0034935-A1 Titanium trichloride catalyst and process for production of alpha-olefin polymers SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1981-09-02 EP claimed
US-4183824-A COORINATION CATALYSTS CONTAINING TITANIUM AND ALUMINUM SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1980-01-15 US claimed
US-4167415-A Photocurable composition comprising copolymer of maleic acid monoester and α-olefin compound KANSAI PAINT CO., LTD. (JP) 1979-09-11 US claimed
US-4092172-A Photocurable composition comprising a copolymer of a maleic acid monoester with an α-olefine KANSAI PAINT CO., LTD. (JA) 1978-05-30 US claimed
US-3954584-A Photopolymerizable vinylurethane liquid composition KANSAI PAINT COMPANY (JA) 1976-05-04 US claimed