SCHEMBL2239244

SCHEMBL2239244

CC=CC(=O)OCCC[Si](CCC)(OC(C)C)OC(C)C

nearest known ligand 0.45

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.45
HCAR2 Q8TDS4 4/20 0.41
MAPT P10636 1/20 0.39
RAB9A P51151 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
HPGD P15428 1/20 0.36
TSHR P16473 1/20 0.36
APP P05067 5/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28573362 0.94 ATM (0.49) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL1269733 0.90 ATM (0.42) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL1270109 0.84 ATM (0.49) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL1269950 0.82 ATM (0.47) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL2246411 0.82 ATM (0.47) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL133183 0.82 ATM (0.42) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL2246326 0.81 ATM (0.54) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL229829 0.81 ATM (0.41) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL853573 0.81 ATM (0.41) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL8899382 0.79 ATM (0.50) ATMHCAR2MAPTRAB9ANPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7994250-B2 Vinyl-urethane copolymers with intermediary linkage segments having silicon-oxygen bonds and production methods thereof KONISHI CO., LTD. (JP) 2011-08-09 US disclosed
US-20090326151-A1 HAIR COSMETIC KONISHI CO., LTD. (JP) 2009-12-31 US disclosed
EP-2039347-A1 COSMETIC HAIR PREPARATION Shiseido Company, Limited (JP) 2009-03-25 EP disclosed
EP-1837360-A1 VINYL-URETHANE COPOLYMER AND METHOD FOR PRODUCING SAME Konishi Co., Ltd. (JP) 2007-09-26 EP disclosed
US-20070117902-A1 Vinyl-urethane copolymers and production methods thereof KONISHI CO., LTD. (JP) 2007-05-24 US disclosed