Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERBB2 | P04626 | 1/20 | 0.62 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.62 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 2/20 | 0.32 |
| ▸ | ACHE | P22303 | 2/20 | 0.32 |
| ▸ | CNR2 | P34972 | 2/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.30 |
| ▸ | BACE1 | P56817 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22397986 | 1.00 | ERBB2 (0.62) | ERBB2MINK1CA9CYP19A1LMNA | |
| SCHEMBL22397998 | 0.91 | ERBB2 (0.59) | ERBB2MINK1CA9CYP19A1LMNA | |
| SCHEMBL28480665 | 0.91 | ERBB2 (0.59) | ERBB2MINK1CA9CYP19A1LMNA | |
| SCHEMBL6582276 | 0.89 | ERBB2 (0.68) | ERBB2MINK1FFAR1MAPT | |
| SCHEMBL6582279 | 0.89 | ERBB2 (0.68) | ERBB2MINK1FFAR1MAPT | |
| SCHEMBL22398048 | 0.88 | ERBB2 (0.47) | ERBB2MINK1CA9CYP19A1LMNA | |
| SCHEMBL28476214 | 0.88 | ERBB2 (0.47) | ERBB2MINK1CA9CYP19A1LMNA | |
| SCHEMBL22398054 | 0.88 | ERBB2 (0.47) | ERBB2MINK1CA9CYP19A1LMNA | |
| SCHEMBL22398043 | 0.88 | ERBB2 (0.47) | ERBB2MINK1CA9CYP19A1LMNA | |
| SCHEMBL22397950 | 0.88 | ERBB2 (0.74) | ERBB2MINK1CYP19A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111886234-B | Heterocyclic mitochondrial activity inhibitors and uses thereof | 蒙特利尔大学 | 2023-12-15 | — | — | CN | disclosed |
| CN-111886234-A | Heterocyclic mitochondrial activity inhibitors and uses thereof | 蒙特利尔大学 | 2020-11-03 | — | — | CN | disclosed |
| EP-3704111-A1 | HETEROCYCLIC MITOCHONDRIAL ACTIVITY INHIBITORS AND USES THEREOF | Université de Montréal (CA) | 2020-09-09 | — | — | EP | disclosed |