Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 2/20 | 0.52 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | GPR84 | Q9NQS5 | 8/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | FDPS | P14324 | 4/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2240815 | 1.00 | FFAR1 (0.52) | FFAR1FFAR4NFKB1GPR84ALDH1A1 | |
| SCHEMBL11616864 | 0.98 | FFAR1 (0.55) | FFAR1FFAR4NFKB1GPR84ALDH1A1 | |
| SCHEMBL11658308 | 0.92 | — | — | |
| SCHEMBL11515234 | 0.90 | FFAR1 (0.52) | FFAR1FFAR4NFKB1GPR84ALDH1A1 | |
| SCHEMBL11601532 | 0.88 | FFAR1 (0.55) | FFAR1FFAR4NFKB1GPR84ALDH1A1 | |
| SCHEMBL30787358 | 0.87 | FFAR1 (0.62) | FFAR1FFAR4NFKB1GPR84FDPS | |
| SCHEMBL327431 | 0.87 | FFAR1 (0.62) | FFAR1FFAR4NFKB1GPR84FDPS | |
| SCHEMBL11619185 | 0.85 | TSHR (0.50) | FFAR1FFAR4NFKB1GPR84ALDH1A1 | |
| SCHEMBL23789287 | 0.84 | FFAR1 (0.67) | FFAR1FFAR4NFKB1GPR84FDPS | |
| SCHEMBL7203318 | 0.84 | FFAR1 (0.67) | FFAR1FFAR4NFKB1GPR84FDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2348120-B1 | Enzymatic reduction of 1-phenylpropanone and derivatives thereof | Universität Wien (AT) | 2014-06-11 | — | — | EP | disclosed |
| EP-2348120-A1 | Enzymatic reduction of 1-phenylpropanone and derivatives thereof | Universität Wien (AT) | 2011-07-27 | — | — | EP | disclosed |