Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL6 | P41182 | 20/20 | 0.52 |
| ▸ | NCOR2 | Q9Y618 | 5/20 | 0.52 |
| ▸ | MELK | Q14680 | 1/20 | 0.52 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
| ▸ | BCL6B | Q8N143 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20284711 | 0.92 | BCL6 (0.63) | BCL6NCOR2MELKCHRM4BCL6B | |
| SCHEMBL20284377 | 0.81 | BCL6 (0.65) | BCL6NCOR2MELKCHRM4BCL6B | |
| SCHEMBL20284524 | 0.81 | BCL6 (0.61) | BCL6NCOR2MELKCHRM4BCL6B | |
| SCHEMBL20284211 | 0.81 | BCL6 (0.76) | BCL6NCOR2MELKCHRM4BCL6B | |
| SCHEMBL20284721 | 0.79 | BCL6 (0.74) | BCL6NCOR2MELKCHRM4BCL6B | |
| SCHEMBL20284386 | 0.78 | BCL6 (0.72) | BCL6NCOR2MELKCHRM4BCL6B | |
| SCHEMBL20284569 | 0.78 | BCL6 (0.68) | BCL6NCOR2MELKCHRM4BCL6B | |
| SCHEMBL20284525 | 0.78 | BCL6 (0.62) | BCL6NCOR2MELKCHRM4BCL6B | |
| SCHEMBL20284527 | 0.78 | BCL6 (0.64) | BCL6NCOR2MELKCHRM4BCL6B | |
| SCHEMBL20284526 | 0.78 | BCL6 (0.66) | BCL6NCOR2MELKCHRM4BCL6B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3555063-B1 | 6-AMINO-QUINOLINONE COMPOUNDS AND DERIVATIVES AS BCL6 INHIBITORS | BOEHRINGER INGELHEIM INT (DE) | 2020-09-16 | — | — | EP | disclosed |