Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | METAP2 | P50579 | 2/20 | 0.33 |
| ▸ | KLK7 | P49862 | 1/20 | 0.33 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1034819 | 0.86 | NT5E (0.37) | NT5ELMNAALDH1A1CYP2D6MAPK1 | |
| SCHEMBL12757246 | 0.86 | NT5E (0.37) | NT5ELMNAALDH1A1CYP2D6MAPK1 | |
| SCHEMBL22423316 | 0.86 | NT5E (0.37) | NT5ELMNAALDH1A1CYP2D6MAPK1 | |
| SCHEMBL2485383 | 0.82 | NT5E (0.53) | NT5EBCHE | |
| SCHEMBL7169887 | 0.82 | NT5E (0.53) | NT5EBCHE | |
| SCHEMBL24672154 | 0.82 | NT5E (0.53) | NT5EBCHE | |
| SCHEMBL21537642 | 0.82 | NT5E (0.53) | NT5EBCHE | |
| SCHEMBL7170086 | 0.82 | NT5E (0.53) | NT5EBCHE | |
| SCHEMBL14598383 | 0.82 | NT5E (0.53) | NT5EBCHE | |
| SCHEMBL19731854 | 0.82 | NT5E (0.53) | NT5EBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3274358-B1 | VACCINE AGAINST CARBAPENEM-RESISTANTKLEBSIELLA PNEUMONIAE | MAX-PLANCK-GESELLSCHAFT ZUR FÖRDERUNG DER WSS EV (DE) | 2020-09-16 | — | — | EP | disclosed |