Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 9/20 | 0.48 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.41 |
| ▸ | CTSS | P25774 | 2/20 | 0.36 |
| ▸ | CTSK | P43235 | 2/20 | 0.36 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
| ▸ | ITGAV | P06756 | 1/20 | 0.36 |
| ▸ | ITGB6 | P18564 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 2/20 | 0.35 |
| ▸ | CTSL | P07711 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22143906 | 1.00 | AAK1 (0.48) | AAK1CACNA1BCTSSCTSKCTSB | |
| SCHEMBL22143702 | 1.00 | AAK1 (0.48) | AAK1CACNA1BCTSSCTSKCTSB | |
| SCHEMBL22143651 | 1.00 | AAK1 (0.48) | AAK1CACNA1BCTSSCTSKCTSB | |
| SCHEMBL22409744 | 1.00 | AAK1 (0.48) | AAK1CACNA1BCTSSCTSKCTSB | |
| SCHEMBL24875529 | 0.94 | AAK1 (0.49) | AAK1CACNA1BCTSSCTSKCTSB | |
| SCHEMBL22143557 | 0.94 | AAK1 (0.49) | AAK1CACNA1BCTSSCTSKCTSB | |
| SCHEMBL22425329 | 0.94 | AAK1 (0.49) | AAK1CACNA1BCTSSCTSKCTSB | |
| SCHEMBL22143552 | 0.94 | AAK1 (0.49) | AAK1CACNA1BCTSSCTSKCTSB | |
| SCHEMBL30192882 | 0.94 | AAK1 (0.49) | AAK1CACNA1BCTSSCTSKCTSB | |
| SCHEMBL29231854 | 0.94 | AAK1 (0.49) | AAK1CACNA1BCTSSCTSKCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020182666-A1 | SMALL MOLECULE MODULATORS OF IL-17 | LEO PHARMA A/S (DK) | 2020-09-17 | — | — | WO | disclosed |