Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR4 | P31391 | 1/20 | 0.49 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 7/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 7/20 | 0.36 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.34 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | PLK1 | P53350 | 1/20 | 0.32 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.32 |
| ▸ | PLK3 | Q9H4B4 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CDK1 | P06493 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25598688 | 1.00 | SSTR4 (0.49) | SSTR4LRRK2DRD4DRD3ALDH1A1 | |
| SCHEMBL10182912 | 0.98 | SSTR4 (0.50) | SSTR4LRRK2DRD4DRD3ALDH1A1 | |
| SCHEMBL18179471 | 0.93 | SSTR4 (0.45) | SSTR4LRRK2DRD4DRD3ALDH1A1 | |
| SCHEMBL21937741 | 0.79 | SSTR4 (0.47) | SSTR4LRRK2DRD4DRD3CYP11B1 | |
| SCHEMBL23762577 | 0.76 | LRRK2 (0.35) | SSTR4LRRK2MEN1MAPTKMT2A | |
| SCHEMBL20861635 | 0.76 | CYP11B1 (0.43) | SSTR4LRRK2DRD4DRD3ALDH1A1 | |
| SCHEMBL18338368 | 0.76 | DRD4 (0.41) | SSTR4LRRK2DRD4DRD3ALDH1A1 | |
| SCHEMBL25772023 | 0.76 | CYP11B1 (0.43) | SSTR4LRRK2DRD4DRD3ALDH1A1 | |
| SCHEMBL23762860 | 0.75 | LRRK2 (0.37) | SSTR4LRRK2SIGMAR1 | |
| SCHEMBL12775911 | 0.75 | DRD4 (0.45) | SSTR4LRRK2DRD4DRD3CYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020185606-A1 | MACROCYCLIC COMPOUNDS | ZENO MANAGEMENT, INC. (US) | 2020-09-17 | — | — | WO | disclosed |