Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLCO1B1 | Q9Y6L6 | 7/20 | 0.70 |
| ▸ | ABCB11 | O95342 | 3/20 | 0.55 |
| ▸ | LPAR1 | Q92633 | 5/20 | 0.47 |
| ▸ | ABCC3 | O15438 | 2/20 | 0.47 |
| ▸ | ABCC4 | O15439 | 2/20 | 0.47 |
| ▸ | SLCO1B3 | Q9NPD5 | 2/20 | 0.47 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.36 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.36 |
| ▸ | BTK | Q06187 | 1/20 | 0.35 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
| ▸ | FURIN | P09958 | 2/20 | 0.34 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19715602 | 0.91 | SLCO1B1 (0.71) | SLCO1B1ABCB11LPAR1ABCC3ABCC4 | |
| SCHEMBL22252461 | 0.88 | SLCO1B1 (0.76) | SLCO1B1ABCB11LPAR1ABCC3ABCC4 | |
| SCHEMBL21097525 | 0.88 | SLCO1B1 (0.56) | SLCO1B1ABCB11LPAR1ABCC3ABCC4 | |
| SCHEMBL28498862 | 0.88 | SLCO1B1 (0.56) | SLCO1B1ABCB11LPAR1ABCC3ABCC4 | |
| SCHEMBL23697798 | 0.88 | SLCO1B1 (0.56) | SLCO1B1ABCB11LPAR1ABCC3ABCC4 | |
| SCHEMBL22252454 | 0.87 | SLCO1B1 (0.71) | SLCO1B1ABCB11LPAR1ABCC3ABCC4 | |
| SCHEMBL21058139 | 0.87 | SLCO1B1 (0.72) | SLCO1B1ABCB11LPAR1ABCC3ABCC4 | |
| SCHEMBL22252457 | 0.86 | SLCO1B1 (0.68) | SLCO1B1ABCB11LPAR1ABCC3ABCC4 | |
| SCHEMBL22436300 | 0.85 | SLCO1B1 (0.64) | SLCO1B1ABCB11LPAR1ABCC3ABCC4 | |
| SCHEMBL22252458 | 0.85 | SLCO1B1 (0.69) | SLCO1B1ABCB11LPAR1ABCC3ABCC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3728223-B1 | CYCLOHEXYL ACID TRIAZOLE AZINES AS LPA ANTAGONISTS | BRISTOL MYERS SQUIBB CO (US) | 2022-12-28 | — | — | EP | disclosed |
| US-20210230143-A1 | CYCLOHEXYL ACID TRIAZOLE AZINES AS LPA ANTAGONISTS | BRISTOL MYERS SQUIBB CO (US) | 2021-07-29 | — | — | US | disclosed |
| EP-3710438-A1 | TRIAZOLE N-LINKED CARBAMOYL CYCLOHEXYL ACIDS AS LPA ANTAGONISTS | Bristol-Myers Squibb Company (US) | 2020-09-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210230143-A1 | CYCLOHEXYL ACID TRIAZOLE AZINES AS LPA ANTAGONISTS | LPAR3, LPAR1, LPAR2 | SLCO1B1 1638/4885ABCB11 1865/4885LPAR1 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.