SCHEMBL22440

SCHEMBL22440

CNC(C)=N

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dimethylamine SCHEMBL28085264 0.95
Hydrochloric Acid SCHEMBL3526529 0.95
Acetamidine SCHEMBL11033535 0.84 MAPK1 (0.32)
SCHEMBL1969697 0.74
SCHEMBL13113558 0.73
SCHEMBL12994077 0.73
SCHEMBL16154147 0.70
SCHEMBL8297624 0.70
SCHEMBL35024 0.70
SCHEMBL25546918 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2227 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2609107-B1 BLOCK SYNTHESIS OF OLIGORIBONUCLEOTIDES THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING / MCGILL UNIV (CA) 2024-12-11 EP claimed
CN-109563121-B 5' S-LNA nucleotides and oligonucleotides 罗氏创新中心哥本哈根有限公司 2022-12-27 CN claimed
US-20220403435-A1 Increasing Long-Sequence Yields In Template-Free Enzymatic Synthesis of Polynucleotides DNA SCRIPT (FR) 2022-12-22 US claimed
EP-4007816-A1 INCREASING LONG-SEQUENCE YIELDS IN TEMPLATE-FREE ENZYMATIC SYNTHESIS OF POLYNUCLEOTIDES DNA Script (FR) 2022-06-08 EP claimed
CN-114430778-A Increasing the yield of long sequences in template-free enzymatic synthesis of polynucleotides DNA斯克瑞普特公司 2022-05-03 CN claimed
US-20210300954-A1 IONIC TAGS FOR SYNTHESIS OF OLIGORIBONUCLEOTIDES THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIV (CA) 2021-09-30 US claimed
CN-113454063-A 3-substituted phenylamidine compounds, preparation method and application thereof PI工业有限公司 2021-09-28 CN claimed
WO-2021018921-A1 INCREASING LONG-SEQUENCE YIELDS IN TEMPLATE-FREE ENZYMATIC SYNTHESIS OF POLYNUCLEOTIDES. DNA SCRIPT (FR) 2021-02-04 WO claimed
EP-3765473-A1 LNA-DICARBOXYLIC ACID DERIVATIVES AND PROCESS FOR THEIR PREPARATION F. Hoffmann-La Roche AG (CH) 2021-01-20 EP claimed
US-10882884-B2 Stereoselective synthesis of phosphorothioate oligoribonucleotides ETH ZURICH (CH) 2021-01-05 US claimed
WO-2000004776-A1 PESTICIDAL COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2000-02-03 WO claimed
EP-0385038-B1 ORTHO-SUBSTITUTED PHENYL AMIDINE AND PHENYL GUANIDINE DERIVATIVES AND ANTIDIABETIC OR HYPOGLYCAEMIC AGENTS CONTAINING THEM The Boots Company PLC (GB) 1993-06-02 EP claimed
EP-0199490-B1 PENEM DERIVATIVES FARMITALIA CARLO ERBA S.r.l. (IT) 1992-09-23 EP claimed
EP-0385038-A1 Ortho-substituted phenyl amidine and phenyl guanidine derivatives and antidiabetic or hypoglycaemic agents containing them The Boots Company PLC (GB) 1990-09-05 EP claimed
EP-0201206-B1 PENEM DERIVATIVES FARMITALIA CARLO ERBA S.r.l. (IT) 1990-07-25 EP claimed
EP-0184384-B1 SUBSTITUTED DIHYDROQUINOLONE CARBOXYLIC ACIDS, ANTI-BACTERIAL COMPOSITIONS CONTAINING THEM PFIZER INC. (US) 1989-08-02 EP claimed
EP-0201206-A1 Penem derivatives FARMITALIA CARLO ERBA S.r.l. (IT) 1986-11-12 EP claimed
EP-0199490-A1 Penem derivatives FARMITALIA CARLO ERBA S.r.l. (IT) 1986-10-29 EP claimed
EP-0184384-A1 Substituted dihydroquinolone carboxylic acids, anti-bacterial compositions containing them PFIZER INC. (US) 1986-06-11 EP claimed
US-4200748-A ANXIOLYTIC AGENTS AMERICAN CYANAMID COMPANY (US) 1980-04-29 US claimed