⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22441287 | 0.87 | GRIN2D (0.52) | — | |
| SCHEMBL23270410 | 0.67 | — | — | |
| SCHEMBL18232321 | 0.64 | — | — | |
| SCHEMBL16039854 | 0.64 | — | — | |
| SCHEMBL15101088 | 0.64 | — | — | |
| SCHEMBL19262511 | 0.64 | — | — | |
| Hydrochloric Acid SCHEMBL13387068 | 0.62 | — | — | |
| Hydrochloric Acid SCHEMBL17837966 | 0.62 | — | — | |
| Hydrochloric Acid SCHEMBL17582395 | 0.62 | — | — | |
| SCHEMBL17097898 | 0.59 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230114107-A1 | COMBINATION ANTI-CANCER THERAPIES WITH INDUCERS OF IRON-DEPENDENT CELLULAR DISASSEMBLY | FLAGSHIP PIONEERING, INC. | 2023-04-13 | — | — | US | disclosed |
| US-20220002280-A1 | COMPOUNDS AND METHODS OF USE | FERRO THERAPEUTICS INC (US) | 2022-01-06 | — | — | US | disclosed |
| WO-2021127217-A1 | COMBINATION ANTI-CANCER THERAPIES WITH INDUCERS OF IRON-DEPENDENT CELLULAR DISASSEMBLY | FLAGSHIP PIONEERING INNOVATIONS V, INC. (US) | 2021-06-24 | — | — | WO | disclosed |
| US-11040964-B2 | Compounds and methods of use | Ferro Therapeutics, Inc. (US) | 2021-06-22 | — | — | US | disclosed |
| US-20200299283-A1 | COMPOUNDS AND METHODS OF USE | BRIDGEBIO PHARMA, INC. | 2020-09-24 | — | — | US | disclosed |