Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.41 |
| ▸ | HPGD | P15428 | 5/20 | 0.41 |
| ▸ | TSHR | P16473 | 4/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.41 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.38 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.38 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | TTR | P02766 | 2/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28693860 | 0.82 | HSP90AB1 (0.43) | HSD17B10HPGDTSHRMAPK1AKR1C2 | |
| SCHEMBL4895488 | 0.77 | HSD17B10 (0.46) | HSD17B10HPGDTSHRMAPK1AKR1C2 | |
| SCHEMBL1513825 | 0.77 | AKR1C2 (0.63) | HSD17B10HPGDTSHRMAPK1AKR1C2 | |
| SCHEMBL10963233 | 0.75 | HSD17B10 (0.44) | HSD17B10HPGDTSHRMAPK1AKR1C2 | |
| SCHEMBL9740619 | 0.73 | AKR1C2 (0.47) | AKR1C2AKR1C1AKR1C4AKR1C3MEN1 | |
| SCHEMBL9739524 | 0.72 | AKR1C2 (0.42) | AKR1C2AKR1C1AKR1C4AKR1C3HIF1A | |
| SCHEMBL5961044 | 0.71 | GAA (0.49) | HSD17B10HPGDTSHRMAPK1MEN1 | |
| SCHEMBL68191 | 0.69 | HSD17B10 (0.77) | HSD17B10HPGDTSHRMAPK1TTR | |
| SCHEMBL30855203 | 0.69 | ERN1 (0.46) | HSD17B10HPGDAKR1C2AKR1C1AKR1C4 | |
| SCHEMBL29334185 | 0.69 | ERN1 (0.46) | HSD17B10HPGDAKR1C2AKR1C1AKR1C4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200299671-A1 | IMMOBILIZED MULTI-ENZYMATIC HALOGENATION SYSTEM | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION | 2020-09-24 | — | — | US | disclosed |