⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12796574 | 0.91 | — | — | |
| SCHEMBL222120 | 0.80 | — | — | |
| SCHEMBL7456 | 0.76 | — | — | |
| SCHEMBL1322917 | 0.76 | — | — | |
| SCHEMBL16007902 | 0.70 | — | — | |
| SCHEMBL9398 | 0.70 | — | — | |
| Fluoride SCHEMBL28168198 | 0.70 | — | — | |
| SCHEMBL4906344 | 0.70 | — | — | |
| SCHEMBL11032589 | 0.70 | TTR (0.50) | — | |
| SCHEMBL14946540 | 0.70 | TTR (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-7173165-A | — | — | None | — | — | JP | disclosed |
| US-12134602-B2 | (−)-huperzine A processes and related compositions and methods of treatment | YALE UNIVERSITY (US) | 2024-11-05 | — | — | US | disclosed |
| US-11485812-B2 | Pyranoquinazoline derivatives and naphthopyran derivatives | KANTO KAGAKU KABUSHIKI KAISHA (JP) | 2022-11-01 | — | — | US | disclosed |
| US-20220064123-A1 | (--)-Huperzine A Processes and Related Compositions and Methods of Treatment | UNIV YALE (US) | 2022-03-03 | — | — | US | disclosed |
| US-11142503-B2 | (−)-huperzine A processes and related compositions and methods of treatment | YALE UNIVERSITY (US) | 2021-10-12 | — | — | US | disclosed |
| US-20200392086-A1 | (--)-Huperzine A Processes and Related Compositions and Methods of Treatment | UNIV YALE (US) | 2020-12-17 | — | — | US | disclosed |
| EP-3434669-B1 | INTERMEDIATE COMPOUNDS UTILIZABLE IN SYNTHESIS OF (-) HUPERZINE AND PROCESS FOR OBTAIN ONE OF THESE INTERMEDIATE COMPOUNDS | UNIV YALE (US) | 2020-11-04 | — | — | EP | disclosed |
| US-10781179-B2 | (−)-huperzine A processes and related compositions and methods of treatment | YALE UNIVERSITY (US) | 2020-09-22 | — | — | US | disclosed |
| US-20200223860-A1 | THE TOTAL SYNTHESIS OF GLUCOSEPANE AND RELATED CHEMICAL REACTIONS, COMPOUNDS AND COMPOSITIONS AND OBTAINED THEREFROM AND METHODS OF TREATMENT | UNIV YALE (US) | 2020-07-16 | — | — | US | disclosed |
| US-20200131193-A1 | PYRANOQUINAZOLINE DERIVATIVES AND NAPHTHOPYRAN DERIVATIVES | KANTO KAGAKU KABUSHIKI KAISHA (JP) | 2020-04-30 | — | — | US | disclosed |
| US-20120004197-A1 | PROPHYLACTIC AND/OR THERAPEUTIC AGENT FOR ANEMIA COMPRISING TETRAHYDROQUINOLINE COMPOUND AS ACTIVE INGREDIENT | KOWA COMPANY, LTD. (JP) | 2012-01-05 | — | — | US | disclosed |
| US-20110060112-A1 | ACRYLATE ESTER DERIVATIVES AND POLYMER COMPOUNDS | KURARAY CO., LTD. (JP) | 2011-03-10 | — | — | US | disclosed |
| US-20110060112-A1 | ACRYLATE ESTER DERIVATIVES AND POLYMER COMPOUNDS | KURARAY CO., LTD. (JP) | 2011-03-10 | — | — | US | disclosed |
| WO-2010114919-A2 | METNASE AND INTNASE INHIBITORS AND THEIR USE IN TREATING CANCER | STC.UNM (US) | 2010-10-07 | — | — | WO | disclosed |
| US-20100222347-A1 | PROPHYLACTIC AND/OR THERAPEUTIC AGENT FOR ANEMIA, COMPRISING TETRAHYDROQUINOLINE COMPOUND AS ACTIVE INGREDIENT | KOWA COMPANY, LTD. (JP) | 2010-09-02 | — | — | US | disclosed |
| EP-2199283-A1 | PROPHYLACTIC AND/OR THERAPEUTIC AGENT FOR ANEMIA, COMPRISING TETRAHYDROQUINOLINE COMPOUND AS ACTIVE INGREDIENT | Kowa Company, Ltd. (JP) | 2010-06-23 | — | — | EP | disclosed |
| US-20090233900-A1 | 2-AMINOBENZAMIDE DERIVATIVE | ASTELLAS PHARMA INC. (JP) | 2009-09-17 | — | — | US | disclosed |
| EP-1955697-A1 | 2-AMINOBENZAMIDE DERIVATIVE | Astellas Pharma Inc. (JP) | 2008-08-13 | — | — | EP | disclosed |
| US-20050250951-A1 | Chiral C2-symmetric biphenyls, their preparation and also metal complexes in which these ligands are present and their use as catalysts in chirogenic syntheses | CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH (DE) | 2005-11-10 | — | — | US | disclosed |
| JP-H07173165-A | PHTHALONITRILE, METAL PHTHALOCYANINE COMPOUND AND THEIR PRODUCTION | NIPPON TELEGR & TELEPH CORP <NTT> | 1995-07-11 | — | — | JP | disclosed |