Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM2 | Q00987 | 7/20 | 0.56 |
| ▸ | MDM4 | O15151 | 3/20 | 0.51 |
| ▸ | TP53 | P04637 | 3/20 | 0.51 |
| ▸ | TNF | P01375 | 1/20 | 0.49 |
| ▸ | TLR2 | O60603 | 2/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3230219 | 0.90 | MDM2 (0.53) | MDM2MDM4TP53TNFCASP3 | |
| SCHEMBL799782 | 0.90 | MDM2 (0.53) | MDM2MDM4TP53TNFCASP3 | |
| SCHEMBL30229489 | 0.90 | MDM2 (0.53) | MDM2MDM4TP53TNFCASP3 | |
| SCHEMBL3728111 | 0.90 | MDM2 (0.53) | MDM2MDM4TP53TNFCASP3 | |
| SCHEMBL31369702 | 0.90 | MDM2 (0.49) | MDM2MDM4TP53TNFTLR2 | |
| SCHEMBL22444788 | 0.89 | MDM2 (0.63) | MDM2MDM4TP53TNFTLR2 | |
| SCHEMBL22444972 | 0.89 | MDM2 (0.63) | MDM2MDM4TP53TNFTLR2 | |
| SCHEMBL28741610 | 0.89 | MDM4 (0.46) | MDM2MDM4TP53TNF | |
| SCHEMBL22444691 | 0.88 | MDM2 (0.54) | MDM2MDM4TP53TNFTLR2 | |
| SCHEMBL26009075 | 0.88 | MDM2 (0.54) | MDM2MDM4TP53TNFTLR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020189540-A1 | METHOD FOR PREPARING AROMATIC AMINO ACID DERIVATIVE | 中外製薬株式会社 | 2020-09-24 | — | — | WO | disclosed |