Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 5/20 | 0.45 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.42 |
| ▸ | TNF | P01375 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | MDM4 | O15151 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29634045 | 1.00 | HDAC1 (0.46) | HDAC1HDAC2PTPN1MDM2TNF | |
| SCHEMBL29634006 | 0.91 | PTPN1 (0.48) | HDAC1HDAC2PTPN1MDM2IDO1 | |
| SCHEMBL22444643 | 0.91 | MDM2 (0.49) | MDM2TNFMDM4TP53 | |
| SCHEMBL22454854 | 0.91 | MDM2 (0.49) | MDM2TNFMDM4TP53 | |
| SCHEMBL29709620 | 0.91 | MDM2 (0.49) | MDM2TNFMDM4TP53 | |
| SCHEMBL31072743 | 0.91 | MDM2 (0.49) | MDM2TNFMDM4TP53 | |
| SCHEMBL22444602 | 0.88 | PPARA (0.45) | HDAC1HDAC2KMT2A | |
| SCHEMBL28741600 | 0.88 | MDM4 (0.41) | PTPN1MDM2MDM4TP53 | |
| SCHEMBL29633743 | 0.88 | MDM4 (0.41) | PTPN1MDM2MDM4TP53 | |
| SCHEMBL29277322 | 0.84 | MDM2 (0.49) | MDM2TNFMDM4TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113692401-A | Process for producing aromatic amino acid derivative | 中外制药株式会社 | 2021-11-23 | — | — | CN | disclosed |
| WO-2020189540-A1 | METHOD FOR PREPARING AROMATIC AMINO ACID DERIVATIVE | 中外製薬株式会社 | 2020-09-24 | — | — | WO | disclosed |