Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM2 | Q00987 | 3/20 | 0.44 |
| ▸ | MDM4 | O15151 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 3/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22454533 | 0.92 | MDM4 (0.43) | MDM2MDM4TP53PTPN1 | |
| SCHEMBL28741433 | 0.92 | MDM4 (0.43) | MDM2MDM4TP53PTPN1 | |
| SCHEMBL29633764 | 0.92 | MDM4 (0.43) | MDM2MDM4TP53PTPN1 | |
| SCHEMBL29633746 | 0.92 | MDM4 (0.43) | MDM2MDM4TP53PTPN1 | |
| SCHEMBL24633854 | 0.91 | MDM2 (0.51) | MDM2MDM4TP53CASP3 | |
| SCHEMBL22444699 | 0.91 | MDM2 (0.51) | MDM2MDM4TP53CASP3 | |
| SCHEMBL31369983 | 0.91 | MDM2 (0.51) | MDM2MDM4TP53CASP3 | |
| SCHEMBL29855552 | 0.91 | MDM2 (0.51) | MDM2MDM4TP53CASP3 | |
| SCHEMBL22444895 | 0.90 | MDM4 (0.45) | MDM2MDM4TP53PTPN1CASP3 | |
| SCHEMBL22444938 | 0.90 | HDAC1 (0.48) | MDM2MDM4TP53PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113692401-A | Process for producing aromatic amino acid derivative | 中外制药株式会社 | 2021-11-23 | — | — | CN | disclosed |
| WO-2020189540-A1 | METHOD FOR PREPARING AROMATIC AMINO ACID DERIVATIVE | 中外製薬株式会社 | 2020-09-24 | — | — | WO | disclosed |