Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7922509 | 0.80 | CYP1A2 (0.32) | — | |
| SCHEMBL21353345 | 0.75 | AKR1B1 (0.44) | AKR1B1DYRK1A | |
| SCHEMBL20595571 | 0.75 | AKR1B1 (0.44) | AKR1B1DYRK1A | |
| SCHEMBL20595570 | 0.75 | AKR1B1 (0.44) | AKR1B1DYRK1A | |
| SCHEMBL20595579 | 0.73 | AKR1B1 (0.43) | AKR1B1DYRK1A | |
| SCHEMBL20595580 | 0.73 | AKR1B1 (0.43) | AKR1B1DYRK1A | |
| SCHEMBL21353636 | 0.73 | AKR1B1 (0.43) | AKR1B1DYRK1A | |
| SCHEMBL31378896 | 0.66 | AKR1B1 (0.42) | AKR1B1IDO1 | |
| SCHEMBL10280632 | 0.64 | AKR1B1 (0.44) | AKR1B1DYRK1ASMN1; SMN2IDO1HTT | |
| SCHEMBL31310986 | 0.63 | SMN1; SMN2 (0.34) | MAPTDYRK1ASMN1; SMN2IDO1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3712143-A1 | QUINAZOLINONE COMPOUND AND APPLICATION THEREOF | Luoxin Pharmaceutical (Shanghai) Co., Ltd. (CN) | 2020-09-23 | — | — | EP | disclosed |